Alternative RNA splicing in the nervous system

Tissue-specific alternative splicing profoundly effects animal physiology, development and disease, and this is nowhere more evident than in the nervous system. Alternative splicing is a versatile form of genetic control whereby a common pre-mRNA is processed into multiple mRNA isoforms differing in...

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Veröffentlicht in:	Progress in neurobiology 2001-10, Vol.65 (3), p.289-308
Hauptverfasser:	Grabowski, P J, Black, D L
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative Splicing - physiology Animals Humans Ion Channels - genetics Ion Channels - metabolism Mental Disorders - genetics Mental Disorders - metabolism Neoplasms - genetics Neoplasms - metabolism Nervous System - metabolism Neurodegenerative Diseases - genetics Neurodegenerative Diseases - metabolism Receptors, Neurotransmitter - genetics Receptors, Neurotransmitter - metabolism RNA, Messenger - metabolism RNA-Binding Proteins - metabolism Spliceosomes - metabolism Synapses - metabolism Synaptic Transmission - physiology
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