Nucleus incertus Orexin2 receptors mediate alcohol seeking in rats

Alcoholism is a chronic relapsing disorder and a major global health problem. Stress is a key precipitant of relapse in human alcoholics and in animal models of alcohol seeking. The brainstem nucleus incertus (NI) contains a population of relaxin-3 neurons that are highly responsive to psychological...

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Veröffentlicht in:	Neuropharmacology 2016-11, Vol.110 (Pt A), p.82-91
Hauptverfasser:	Kastman, Hanna E., Blasiak, Anna, Walker, Leigh, Siwiec, Marcin, Krstew, Elena V., Gundlach, Andrew L., Lawrence, Andrew J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Animals Drug-Seeking Behavior - drug effects Drug-Seeking Behavior - physiology Ethanol - administration & dosage Male Microinjections Nucleus incertus Orexin Orexin Receptor Antagonists - administration & dosage Orexin Receptors - physiology Raphe Nuclei - drug effects Raphe Nuclei - physiology Rats Rats, Wistar Reinstatement Relaxin-3 Self Administration Stress Yohimbine - administration & dosage
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