COMPARISON OF C-MYC EXPRESSION IN NORMAL HUMAN BRONCHIAL EPITHELIAL CELLS AND LUNG CANCER CELL LINES USING A QUANTITATIVE FLUORESCENCE-BASED REVERSE TRANSCRIPTASE-POLYMERASE CHAIN REACTION METHOD

Mutations, either heritable or induced,can modulate the expression of oncogenes and/or tumor suppressor genes and thereby alter the biology of the affected cells. Over expression of the c-myc oncogene appears to contribute to the development of small cell lung cancer, and has been used as an indicat...

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Veröffentlicht in:Toxicology mechanisms and methods 1999-07, Vol.9 (3), p.173-188
Hauptverfasser: Fields, Wanda, Bombick, David, Desiderio, Joseph, Doolittle, David
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Sprache:eng
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