Prognostic Value of Programmed Death Ligand 1 and Programmed Death 1 Expression in Thymic Carcinoma

The immune checkpoint of the programmed death 1/programmed death ligand 1 (PD-1/PD-L1) pathway is believed to play an important role in evasion of host antitumor immune surveillance in various malignancies; however, little is known about its role in thymic carcinoma. This study investigated PD-1/PD-...

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Veröffentlicht in:	Clinical cancer research 2016-09, Vol.22 (18), p.4727-4734
Hauptverfasser:	Yokoyama, Shintaro, Miyoshi, Hiroaki, Nakashima, Kazutaka, Shimono, Joji, Hashiguchi, Toshihiro, Mitsuoka, Masahiro, Takamori, Shinzo, Akagi, Yoshito, Ohshima, Koichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over B7-H1 Antigen - genetics B7-H1 Antigen - metabolism Biomarkers, Tumor Carcinoma - diagnosis Carcinoma - genetics Carcinoma - mortality Carcinoma - therapy Female Gene Dosage Gene Expression Humans Immunohistochemistry Kaplan-Meier Estimate Lymphocyte Count Male Middle Aged Neoplasm Staging Programmed Cell Death 1 Receptor - genetics Programmed Cell Death 1 Receptor - metabolism T-Lymphocytes, Cytotoxic - immunology T-Lymphocytes, Cytotoxic - metabolism Thymus Neoplasms - diagnosis Thymus Neoplasms - genetics Thymus Neoplasms - mortality Thymus Neoplasms - therapy
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