Inactivation of a gene that is highly conserved in Gram‐positive bacteria stimulates degradation of non‐native proteins and concomitantly increases stress tolerance in Lactococcus lactis

Exposure of cells to elevated temperatures triggers the synthesis of chaperones and proteases including components of the conserved Clp protease complex. We demonstrated previously that the proteolytic subunit, ClpP, plays a major role in stress tolerance and in the degradation of non‐native protein...

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Veröffentlicht in:Molecular microbiology 2001-07, Vol.41 (1), p.93-103
Hauptverfasser: Frees, Dorte, Varmanen, Pekka, Ingmer, Hanne
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Sprache:eng
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