The immune receptor Tim-3 acts as a trafficker in a Tim-3/galectin-9 autocrine loop in human myeloid leukemia cells

The immune receptor Tim-3 is often highly expressed in human acute myeloid leukemia (AML) cells where it acts as a growth factor and inflammatory receptor. Recently, it has been demonstrated that Tim-3 forms an autocrine loop with its natural ligand galectin-9 in human AML cells. However, the pathop...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Oncoimmunology 2016-07, Vol.5 (7), p.e1195535-e1195535
Hauptverfasser:	Gonçalves Silva, Isabel, Rüegg, Laura, Gibbs, Bernhard F., Bardelli, Marco, Fruehwirth, Alexander, Varani, Luca, Berger, Steffen M., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute myeloid leukemia galectin-9 Original Research Tim-3
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!