ATDC/TRIM29 Drives Invasive Bladder Cancer Formation through miRNA-Mediated and Epigenetic Mechanisms

Bladder cancer is a common and deadly malignancy but its treatment has advanced little due to poor understanding of the factors and pathways that promote disease. ATDC/TRIM29 is a highly expressed gene in several lethal tumor types, including bladder tumors, but its role as a pathogenic driver has n...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2015-12, Vol.75 (23), p.5155-5166
Hauptverfasser:	Palmbos, Phillip L, Wang, Lidong, Yang, Huibin, Wang, Yin, Leflein, Jacob, Ahmet, McKenzie L, Wilkinson, John E, Kumar-Sinha, Chandan, Ney, Gina M, Tomlins, Scott A, Daignault, Stephanie, Kunju, Lakshmi P, Wu, Xue-Ru, Lotan, Yair, Liebert, Monica, Ljungman, Mats E, Simeone, Diane M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line, Tumor Disease Models, Animal DNA (Cytosine-5-)-Methyltransferases - genetics DNA (Cytosine-5-)-Methyltransferases - metabolism DNA-Binding Proteins - biosynthesis DNA-Binding Proteins - genetics Epigenesis, Genetic Female Gene Expression Humans Mice Mice, Inbred NOD Mice, SCID Mice, Transgenic MicroRNAs - genetics MicroRNAs - metabolism Neoplasm Invasiveness PTEN Phosphohydrolase - genetics PTEN Phosphohydrolase - metabolism Transcription Factors - biosynthesis Transcription Factors - genetics Transfection Up-Regulation Urinary Bladder Neoplasms - genetics Urinary Bladder Neoplasms - metabolism Urinary Bladder Neoplasms - pathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!