A population based study comparing changes in rotavirus burden on the Island of Ireland between a highly vaccinated population and an unvaccinated population

Highlights • Ecological study of impact of rotavirus vaccine on the Island of Ireland. • Rotavirus vaccine was introduced in Northern Ireland only. • Ireland was in effect an unvaccinated control population. • Significant reduction in rotavirus burden in NI, with concurrent increase in Ireland. • Re...

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Veröffentlicht in:Vaccine 2016-09, Vol.34 (39), p.4718-4723
Hauptverfasser: Armstrong, Gillian, Gallagher, Naomh, Cabrey, Paul, Graham, Adele M, McKeown, Paul J, Jackson, Sarah, Dallat, Mary, Smithson, Richard D
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Sprache:eng
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Zusammenfassung:Highlights • Ecological study of impact of rotavirus vaccine on the Island of Ireland. • Rotavirus vaccine was introduced in Northern Ireland only. • Ireland was in effect an unvaccinated control population. • Significant reduction in rotavirus burden in NI, with concurrent increase in Ireland. • Reduction in rotavirus burden is likely to be attributable to the rotavirus vaccine.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2016.08.004