Amplification of Long Noncoding RNA ZFAS1 Promotes Metastasis in Hepatocellular Carcinoma

Despite progress in the diagnostics and treatment of hepatocellular carcinoma (HCC), its prognosis remains poor. In this study, we globally assessed long noncoding RNAs (lncRNA) for contributions to HCC using publicly available microarray data, in vitro and in vivo assays. Here, we report that ZFAS1...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2015-08, Vol.75 (15), p.3181-3191
Hauptverfasser:	Li, Tao, Xie, Junjie, Shen, Chuan, Cheng, Dongfeng, Shi, Yuan, Wu, Zhichong, Deng, Xiaxing, Chen, Hao, Shen, Baiyong, Peng, Chenghong, Li, Hongwei, Zhan, Qian, Zhu, Zhecheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - mortality Carcinoma, Hepatocellular - pathology Cell Line, Tumor Gene Expression Regulation, Neoplastic Homeodomain Proteins - genetics Humans Liver Neoplasms - genetics Liver Neoplasms - mortality Liver Neoplasms - pathology Matrix Metalloproteinase 14 - genetics Matrix Metalloproteinase 16 - genetics Mice, Inbred BALB C MicroRNAs - genetics Prognosis RNA, Long Noncoding - genetics Transcription Factors - genetics Xenograft Model Antitumor Assays Zinc Finger E-box-Binding Homeobox 1
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