Arabidopsis thalianaMRE11 is essential for activation of cell cycle arrest, transcriptional regulation and DNA repair upon the induction of double-stranded DNA breaks

Given the fundamental role of MRE11 in many aspects of DNA metabolism and signalling in eukaryotes, we analysed the impact of several MRE11 mutations on DNA damage response (DDR) and DNA repair in Arabidopsis thaliana. Three different atmre11 and an atatm-2 mutant lines, together with the wild type...

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Veröffentlicht in:	Plant biology (Stuttgart, Germany) Germany), 2016-07, Vol.18 (4), p.681-694
Hauptverfasser:	Šamanić, I., Cvitanić, R., Simunić, J., Puizina, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	1::GUS Arabidopsis Arabidopsis - cytology Arabidopsis - genetics Arabidopsis - physiology Arabidopsis Proteins - genetics Arabidopsis Proteins - metabolism Arabidopsis thaliana ataxia telangiectasia-mutated atmre1 mutants Cell Cycle Checkpoints Chromosome Aberrations CYCB1 DNA Breaks, Double-Stranded DNA Damage DNA damage response DNA Repair DNA, Plant - genetics DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Gene Expression Regulation, Plant Genes, Reporter genome instability Genome, Plant - genetics MRE11 Homologue Protein Mutation
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