Wastewater treatment plant effluent alters pituitary gland gonadotropin mRNA levels in juvenile coho salmon (Oncorhynchus kisutch)

⿢In this study we examined pituitary lhb and fshb as markers of estrogen exposure.⿢Acute 2ngL⿿1 EE2 exposure induced pituitary lhb but not liver vtg in juvenile fish.⿢Pituitary lhb but not vtg was induced in fish exposed to 5 of 8 WWTP effluents.⿢Lhb mRNA levels may be a sensitive index of estrogeni...

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Veröffentlicht in:	Aquatic toxicology 2016-09, Vol.178, p.118-131
Hauptverfasser:	Harding, Louisa B., Schultz, Irvin R., da Silva, Denis A.M., Ylitalo, Gina M., Ragsdale, Dave, Harris, Stephanie I., Bailey, Stephanie, Pepich, Barry V., Swanson, Penny
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Endocrine disrupting compound Endocrine Disruptors - toxicity Ethinyl Estradiol - toxicity Female Follicle Stimulating Hormone - genetics Follicle Stimulating Hormone - metabolism Follicle-stimulating hormone Gene Expression - drug effects Gonadotropin Gonadotropins, Pituitary - genetics Gonadotropins, Pituitary - metabolism Luteinizing hormone Luteinizing Hormone - genetics Luteinizing Hormone - metabolism Oncorhynchus kisutch Oncorhynchus kisutch - growth & development Oncorhynchus kisutch - metabolism Pituitary Pituitary Gland - drug effects Pituitary Gland - metabolism RNA, Messenger - metabolism Trenbolone Acetate - toxicity Vitellogenin Waste Disposal, Fluid Wastewater effluent Water Pollutants, Chemical - toxicity
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