Impact of early treatment programs on HIV epidemics: An immunity-based mathematical model

•We develop an immunity-based mathematical model for HIV dynamics.•We define and quantify the community-level immunity of HIV epidemics.•Early treatment can significantly improve the community-level immunity.•We evaluate the impact of early treatment programs on HIV disease outcomes.•The treatment b...

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Veröffentlicht in:	Mathematical biosciences 2016-10, Vol.280, p.38-49
Hauptverfasser:	Rahman, S.M. Ashrafur, Vaidya, Naveen K., Zou, Xingfu
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiretroviral therapy Antirheumatic Agents - therapeutic use Basic reproduction number CD4+ T cell count CD4-Positive T-Lymphocytes Community-level immunity Epidemics - statistics & numerical data HIV HIV Infections - epidemiology HIV Infections - immunology HIV Infections - therapy Humans Models, Theoretical
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