Killing effect of nanoencapsulated colistin sulfate on Pseudomonas aeruginosa from cystic fibrosis patients

Abstract Pseudomonas aeruginosa frequently infects the respiratory tract of cystic fibrosis (CF) patients. Multidrug-resistant phenotypes and high capacity to form stable biofilms are common. Recent studies have described the emergence of colistin-resistant isolates in CF patients treated with long-...

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Veröffentlicht in:	Journal of cystic fibrosis 2016-09, Vol.15 (5), p.611-618
Hauptverfasser:	Sans-Serramitjana, E, Fusté, E, Martínez-Garriga, B, Merlos, A, Pastor, M, Pedraz, J.L, Esquisabel, A, Bachiller, D, Vinuesa, T, Viñas, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - pharmacokinetics Antimicrobial effect Biofilms - drug effects Child Colistin - administration & dosage Colistin - pharmacokinetics Colistin sulfate Cystic fibrosis Cystic Fibrosis - diagnosis Cystic Fibrosis - epidemiology Cystic Fibrosis - microbiology Cystic Fibrosis - therapy Drug Delivery Systems - methods Drug Monitoring - methods Drug Resistance, Bacterial - drug effects Female Humans Lipid nanoparticles Male Middle Aged Nanoparticles - administration & dosage Outcome Assessment (Health Care) Pseudomonas aeruginosa Pseudomonas aeruginosa - drug effects Pseudomonas aeruginosa - isolation & purification Pseudomonas aeruginosa - physiology Pseudomonas Infections - diagnosis Pseudomonas Infections - drug therapy Pulmonary/Respiratory Respiratory System - microbiology Respiratory Tract Infections - diagnosis Respiratory Tract Infections - drug therapy Respiratory Tract Infections - microbiology Spain - epidemiology
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