YKL-40 as marker of severe lung disease in cystic fibrosis patients

Abstract Background YKL-40 is a chitinase-like protein present in serum of healthy subjects and its levels are increased in several human inflammatory diseases. The aim of this study was to evaluate the levels of both serum and sputum YKL-40 in cystic fibrosis (CF) patients. Methods Serum and sputum...

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Veröffentlicht in:	Journal of cystic fibrosis 2016-09, Vol.15 (5), p.583-586
Hauptverfasser:	Leonardi, Salvatore, Parisi, Giuseppe Fabio, Capizzi, Antonino, Manti, Sara, Cuppari, Caterina, Scuderi, Maria Grazia, Rotolo, Novella, Lanzafame, Angela, Musumeci, Maria, Salpietro, Carmelo
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute pulmonary exacerbation Adolescent Adult Biomarkers - blood Biomarkers - metabolism Child Chitinase-3-Like Protein 1 - blood Cystic fibrosis Cystic Fibrosis - blood Cystic Fibrosis - physiopathology Disease Progression Female Humans Lung Diseases - blood Lung Diseases - etiology Lung Diseases - physiopathology Lung function decline Male Pulmonary pseudomonas infection Pulmonary/Respiratory Reproducibility of Results Respiratory Function Tests - methods Severity of Illness Index Sputum - metabolism Statistics as Topic Symptom Flare Up YKL-40
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