Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health

Klebsiella pneumoniae is now recognized as an urgent threat to human health because of the emergence of multidrug-resistant strains associated with hospital outbreaks and hypervirulent strains associated with severe community-acquired infections. K. pneumoniae is ubiquitous in the environment and ca...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2015-07, Vol.112 (27), p.E3574-E3581
Hauptverfasser:	Holt, Kathryn E, Wertheim, Heiman, Zadoks, Ruth N, Baker, Stephen, Whitehouse, Chris A, Dance, David, Jenney, Adam, Connor, Thomas R, Hsu, Li Yang, Severin, Juliëtte, Brisse, Sylvain, Cao, Hanwei, Wilksch, Jonathan, Gorrie, Claire, Schultz, Mark B, Edwards, David J, Nguyen, Kinh Van, Nguyen, Trung Vu, Dao, Trinh Tuyet, Mensink, Martijn, Minh, Vien Le, Nhu, Nguyen Thi Khanh, Schultsz, Constance, Kuntaman, Kuntaman, Newton, Paul N, Moore, Catrin E, Strugnell, Richard A, Thomson, Nicholas R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Infective Agents - pharmacology antibiotic resistance Bacterial Proteins - classification Bacterial Proteins - genetics Biological Sciences clones Cloning Cross Infection - microbiology data collection Drug Resistance, Multiple, Bacterial - genetics Genes Genes, Bacterial - genetics Genetic Variation Genome, Bacterial - genetics Genomes genomics Genomics - methods hospitals human diseases human health Humans Klebsiella Infections - microbiology Klebsiella pneumoniae Klebsiella pneumoniae - classification Klebsiella pneumoniae - genetics Klebsiella pneumoniae - pathogenicity Multidrug resistant organisms multiple drug resistance Phylogeny plants (botany) PNAS Plus Population Dynamics population structure Public health Public Health - statistics & numerical data Public Health - trends sequence analysis Sequence Analysis, DNA Species Specificity virulence Virulence - genetics
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