Improved efficiency of remission induction facilitates autologous BMT harvesting and improves overall survival in adults with AML : 108 patients treated at a single institution

A hundred and eight patients less than 60 years old with de novo acute myeloid leukemia were treated between 1982 and 1994 by protocols including final intensification with a transplant using autologous bone marrow purged by mafosfamide in first remission in the absence of an HLA-matched sibling don...

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Veröffentlicht in:	Bone marrow transplantation (Basingstoke) 2001-05, Vol.27 (10), p.1045-1052
Hauptverfasser:	ISNARD, F, GUIGUET, M, AOUDJHANE, M, LOPEZ, M, DOUAY, L, GORIN, N. C, NAJMAN, A, LAPORTE, Jph, ZUNIC, P, ELLOUMI, M, CHERON, N, DELOUX, J, VAN DEN AKKER, J, LESAGE, S, FOUILLARD, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Acute myeloid leukemia Adolescent Adult Amsacrine - administration & dosage Amsacrine - toxicity Anthracycline Antineoplastic agents Antineoplastic Combined Chemotherapy Protocols - administration & dosage Antineoplastic Combined Chemotherapy Protocols - toxicity Autografts Biological and medical sciences Bone marrow Bone marrow transplantation Bone Marrow Transplantation - mortality Bone Marrow Transplantation - standards Chemotherapy Combined treatments (chemotherapy of immunotherapy associated with an other treatment) Consolidation Cytarabine Cytarabine - administration & dosage Cytarabine - toxicity Etoposide - administration & dosage Etoposide - toxicity Feasibility Female Grafting Histocompatibility antigen HLA Humans Karyotypes Leukemia Leukemia, Myeloid - complications Leukemia, Myeloid - mortality Leukemia, Myeloid - therapy Leukocytes Male Medical sciences Middle Aged Multivariate analysis Patients Pharmacology. Drug treatments Remission Remission Induction Retrospective Studies Stem cell transplantation Survival Survival Rate Toxicity Transplantation Transplantation, Autologous - mortality Transplantation, Autologous - standards Transplants & implants Treatment Outcome Tumors
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