Effects of hypothermic deep-anaesthesia on energy metabolism at brain and peripheral levels: a multi-probe microdialysis study in free-moving rat

Reduction of central energy metabolism is a strategy to protect brain against neurotoxic events. The aim of this microdialysis study in rats is to evaluate changes in energy metabolite levels at central level (striatum) comparatively to peripheral level (subcutaneous adipose tissue) during hypotherm...

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Veröffentlicht in:	Neuroscience letters 2001-05, Vol.304 (1), p.21-24
Hauptverfasser:	Lonjon, M., Risso, J.J., Palmier, B., Negrin, J., Darbin, O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Anesthesia - pharmacology Anesthetics. Neuromuscular blocking agents Animals Biological and medical sciences Brain - drug effects Brain - metabolism Energy Metabolism - drug effects Energy Metabolism - physiology Glucose Glucose - metabolism Hypothermia, Induced Lactate Lactic Acid - metabolism Male Medical sciences Microdialysis - methods Neuropharmacology Pentobarbital Pentobarbital - pharmacology Pharmacology. Drug treatments Puruvate Pyruvic Acid - metabolism Rats Rats, Sprague-Dawley Striatum
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