Lipotoxicity pathways intersect in hepatocytes: Endoplasmic reticulum stress, c-Jun N-terminal kinase-1, and death receptors

Non‐alcoholic fatty liver disease (NAFLD) is becoming increasingly more common worldwide. Hepatocyte apoptosis caused by free fatty acids, termed hepatocyte lipoapoptosis, is a feature of non‐alcoholic steatohepatitis (NASH), an advanced form of NAFLD. As no salutary treatment for NASH exists, it is...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Hepatology research 2016-09, Vol.46 (10), p.977-984
Hauptverfasser:	Akazawa, Yuko, Nakao, Kazuhiko
Format:	Artikel
Sprache:	eng
Schlagworte:	apoptosis BH3 interacting domain death agonist protein cell-derived microparticles endoplasmic reticulum stress free fatty acids non-alcoholic steatohepatitis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!