Transcranial Random Noise Stimulation Does Not Enhance the Effects of Working Memory Training

Transcranial random noise stimulation (tRNS), a noninvasive brain stimulation technique, enhances the generalization and sustainability of gains following mathematical training. Here it is combined for the first time with working memory training in a double-blind randomized controlled trial. Adults...

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Veröffentlicht in:Journal of cognitive neuroscience 2016-10, Vol.28 (10), p.1471-1483
Hauptverfasser: Holmes, Joni, Byrne, Elizabeth M., Gathercole, Susan E., Ewbank, Michael P.
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container_issue 10
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container_title Journal of cognitive neuroscience
container_volume 28
creator Holmes, Joni
Byrne, Elizabeth M.
Gathercole, Susan E.
Ewbank, Michael P.
description Transcranial random noise stimulation (tRNS), a noninvasive brain stimulation technique, enhances the generalization and sustainability of gains following mathematical training. Here it is combined for the first time with working memory training in a double-blind randomized controlled trial. Adults completed 10 sessions of Cogmed Working Memory Training with either active tRNS or sham stimulation applied bilaterally to dorsolateral pFC. Training was associated with gains on both the training tasks and on untrained tests of working memory that shared overlapping processes with the training tasks, but not with improvements on working memory tasks with distinct processing demands or tests of other cognitive abilities (e.g., IQ, maths). There was no evidence that tRNS increased the magnitude or transfer of these gains. Thus, combining tRNS with Cogmed Working Memory Training provides no additional therapeutic value.
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subjects Adolescent
Adult
Bayes Theorem
Brain
Cognitive ability
Double-Blind Method
Female
Humans
Learning - physiology
Linear Models
Male
Memory
Memory, Short-Term - physiology
Neuropsychological Tests
Neurosciences
Prefrontal Cortex - physiology
ROC Curve
Transcranial Direct Current Stimulation
Young Adult
title Transcranial Random Noise Stimulation Does Not Enhance the Effects of Working Memory Training
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