Transcranial Random Noise Stimulation Does Not Enhance the Effects of Working Memory Training
Transcranial random noise stimulation (tRNS), a noninvasive brain stimulation technique, enhances the generalization and sustainability of gains following mathematical training. Here it is combined for the first time with working memory training in a double-blind randomized controlled trial. Adults...
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Veröffentlicht in: | Journal of cognitive neuroscience 2016-10, Vol.28 (10), p.1471-1483 |
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creator | Holmes, Joni Byrne, Elizabeth M. Gathercole, Susan E. Ewbank, Michael P. |
description | Transcranial random noise stimulation (tRNS), a noninvasive brain stimulation technique, enhances the generalization and sustainability of gains following mathematical training. Here it is combined for the first time with working memory training in a double-blind randomized controlled trial. Adults completed 10 sessions of Cogmed Working Memory Training with either active tRNS or sham stimulation applied bilaterally to dorsolateral pFC. Training was associated with gains on both the training tasks and on untrained tests of working memory that shared overlapping processes with the training tasks, but not with improvements on working memory tasks with distinct processing demands or tests of other cognitive abilities (e.g., IQ, maths). There was no evidence that tRNS increased the magnitude or transfer of these gains. Thus, combining tRNS with Cogmed Working Memory Training provides no additional therapeutic value. |
doi_str_mv | 10.1162/jocn_a_00993 |
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Here it is combined for the first time with working memory training in a double-blind randomized controlled trial. Adults completed 10 sessions of Cogmed Working Memory Training with either active tRNS or sham stimulation applied bilaterally to dorsolateral pFC. Training was associated with gains on both the training tasks and on untrained tests of working memory that shared overlapping processes with the training tasks, but not with improvements on working memory tasks with distinct processing demands or tests of other cognitive abilities (e.g., IQ, maths). There was no evidence that tRNS increased the magnitude or transfer of these gains. 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Here it is combined for the first time with working memory training in a double-blind randomized controlled trial. Adults completed 10 sessions of Cogmed Working Memory Training with either active tRNS or sham stimulation applied bilaterally to dorsolateral pFC. Training was associated with gains on both the training tasks and on untrained tests of working memory that shared overlapping processes with the training tasks, but not with improvements on working memory tasks with distinct processing demands or tests of other cognitive abilities (e.g., IQ, maths). There was no evidence that tRNS increased the magnitude or transfer of these gains. Thus, combining tRNS with Cogmed Working Memory Training provides no additional therapeutic value.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Bayes Theorem</subject><subject>Brain</subject><subject>Cognitive ability</subject><subject>Double-Blind Method</subject><subject>Female</subject><subject>Humans</subject><subject>Learning - physiology</subject><subject>Linear Models</subject><subject>Male</subject><subject>Memory</subject><subject>Memory, Short-Term - physiology</subject><subject>Neuropsychological Tests</subject><subject>Neurosciences</subject><subject>Prefrontal Cortex - physiology</subject><subject>ROC Curve</subject><subject>Transcranial Direct Current Stimulation</subject><subject>Young Adult</subject><issn>0898-929X</issn><issn>1530-8898</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkc9rFTEQx4Mo9rV68ywBLz24mkmySfZY6vMHVAWt6EVCNpvYPHeTZ7JbqH-9ebwqpfTgZYYJHz4z4YvQEyAvAAR9uUk2aqMJ6Tp2D62gZaRRqlP30YrU1nS0-3aADkvZEEJoK_hDdEAlg5YKuULfz7OJxdYSzIg_mTikCX9IoTj8eQ7TMpo5pIhfJVfq84zX8cJE6_B84fDae2fngpPHX1P-GeIP_N5NKV_hKg2xzo_QA2_G4h5f9yP05fX6_PRtc_bxzbvTk7PGcgVzw3wP4H1rpQeuKB0M7UEqJ0FCO1BnWQf18N5xSQWXTNheUScF54PisufsCB3vvducfi2uzHoKxbpxNNGlpWhQVHYUhFT_gYIQTEjRVvTZLXSTlhzrR3ZUx5niICv1fE_ZnErJzuttDpPJVxqI3iWkbyZU8afX0qWf3PAP_htJBU72wBRuLNw5LqkK1ckI45JrSihUvyad_h22t5cc3-G4854_w5KtgA</recordid><startdate>20161001</startdate><enddate>20161001</enddate><creator>Holmes, Joni</creator><creator>Byrne, Elizabeth M.</creator><creator>Gathercole, Susan E.</creator><creator>Ewbank, Michael P.</creator><general>MIT Press</general><general>MIT Press Journals, The</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QR</scope><scope>7TK</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20161001</creationdate><title>Transcranial Random Noise Stimulation Does Not Enhance the Effects of Working Memory Training</title><author>Holmes, Joni ; Byrne, Elizabeth M. ; Gathercole, Susan E. ; Ewbank, Michael P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c481t-3fb11ff5c7f14822da2b178e71715d2ec391564be47264736cb82e7644d847b43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Bayes Theorem</topic><topic>Brain</topic><topic>Cognitive ability</topic><topic>Double-Blind Method</topic><topic>Female</topic><topic>Humans</topic><topic>Learning - physiology</topic><topic>Linear Models</topic><topic>Male</topic><topic>Memory</topic><topic>Memory, Short-Term - physiology</topic><topic>Neuropsychological Tests</topic><topic>Neurosciences</topic><topic>Prefrontal Cortex - physiology</topic><topic>ROC Curve</topic><topic>Transcranial Direct Current Stimulation</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Holmes, Joni</creatorcontrib><creatorcontrib>Byrne, Elizabeth M.</creatorcontrib><creatorcontrib>Gathercole, Susan E.</creatorcontrib><creatorcontrib>Ewbank, Michael P.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Chemoreception Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cognitive neuroscience</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Holmes, Joni</au><au>Byrne, Elizabeth M.</au><au>Gathercole, Susan E.</au><au>Ewbank, Michael P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Transcranial Random Noise Stimulation Does Not Enhance the Effects of Working Memory Training</atitle><jtitle>Journal of cognitive neuroscience</jtitle><addtitle>J Cogn Neurosci</addtitle><date>2016-10-01</date><risdate>2016</risdate><volume>28</volume><issue>10</issue><spage>1471</spage><epage>1483</epage><pages>1471-1483</pages><issn>0898-929X</issn><eissn>1530-8898</eissn><abstract>Transcranial random noise stimulation (tRNS), a noninvasive brain stimulation technique, enhances the generalization and sustainability of gains following mathematical training. 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subjects | Adolescent Adult Bayes Theorem Brain Cognitive ability Double-Blind Method Female Humans Learning - physiology Linear Models Male Memory Memory, Short-Term - physiology Neuropsychological Tests Neurosciences Prefrontal Cortex - physiology ROC Curve Transcranial Direct Current Stimulation Young Adult |
title | Transcranial Random Noise Stimulation Does Not Enhance the Effects of Working Memory Training |
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