Psychotropic medications in adult and adolescent eating disorders: clinical practice versus evidence-based recommendations

Aim The current study examined the frequency of psychotropic prescriptions in a clinical sample of eating disorder (ED) patients confirming earlier research indicating their use is very common but inconsistent with evidence-based recommendations. Methods The sample consisted of 501 ED patients admit...

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Veröffentlicht in:Eating and weight disorders 2016-09, Vol.21 (3), p.395-402
Hauptverfasser: Garner, David M., Anderson, Michael L., Keiper, Christopher D., Whynott, Rachel, Parker, Lisa
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container_issue 3
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container_title Eating and weight disorders
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creator Garner, David M.
Anderson, Michael L.
Keiper, Christopher D.
Whynott, Rachel
Parker, Lisa
description Aim The current study examined the frequency of psychotropic prescriptions in a clinical sample of eating disorder (ED) patients confirming earlier research indicating their use is very common but inconsistent with evidence-based recommendations. Methods The sample consisted of 501 ED patients admitted to an adult partial hospitalization or adolescent residential program. Patients were divided into two diagnostic groups: anorexia nervosa (AN = 287) and bulimia nervosa (BN = 214), as well as two age groups: adults (age ≥18; N  = 318) and adolescents (age
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Methods The sample consisted of 501 ED patients admitted to an adult partial hospitalization or adolescent residential program. Patients were divided into two diagnostic groups: anorexia nervosa (AN = 287) and bulimia nervosa (BN = 214), as well as two age groups: adults (age ≥18; N  = 318) and adolescents (age &lt;18; N  = 183). Results Forty-one different psychotropic medications (891 prescriptions in all) were prescribed for 429 patients. Overall, 85.6 % of the total sample reported using one or more psychotropic medications. Of 429 patients using any medications, 46.9 % were on two or more, 25.3 % on three or more, and 11.0 % four or more. Antidepressants were most commonly prescribed (89.5 % of those on medication) with no significant differences in usage patterns based on diagnosis. However, there was greater medication use among adults (89.6 %) compared to adolescents (78.7 %). Results indicate psychotropic medication prescription is more widespread in a clinical sample than in an earlier report screening for osteoporosis in AN women. Discussion Treatment recommendations suggest medication should not be the primary treatment for EDs and empirical evidence demonstrates their ineffectiveness in AN. Nevertheless, there were no differences in frequency found between diagnostic groups, confirming little relationship between evidence-based recommendations and actual clinical use for those referred to a specialized ED treatment facility. This study adds new evidence regarding age-based comparisons of psychotropic prescription frequency in clinical EDs and comparison between AN and BN which has not been examined in earlier studies.</description><identifier>ISSN: 1124-4909</identifier><identifier>EISSN: 1590-1262</identifier><identifier>DOI: 10.1007/s40519-016-0253-0</identifier><identifier>PMID: 26830430</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Adolescent ; Adult ; Adults ; Age ; Antidepressive Agents - therapeutic use ; Antipsychotic Agents - therapeutic use ; Child ; Eating disorders ; Evidence-Based Medicine ; Feeding and Eating Disorders - drug therapy ; Female ; Humans ; Male ; Medicine ; Medicine &amp; Public Health ; Middle Aged ; Original Article ; Psychiatry ; Psychotropic drugs ; Psychotropic Drugs - therapeutic use ; Teenagers ; Treatment Outcome ; Young Adult</subject><ispartof>Eating and weight disorders, 2016-09, Vol.21 (3), p.395-402</ispartof><rights>Springer International Publishing Switzerland 2016</rights><rights>Springer International Publishing Switzerland 2016.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c438t-146696a7c124a7bef31c509f9bbc41bbb972073e5aeb7ce5a9a186cd8a77bf153</citedby><cites>FETCH-LOGICAL-c438t-146696a7c124a7bef31c509f9bbc41bbb972073e5aeb7ce5a9a186cd8a77bf153</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s40519-016-0253-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s40519-016-0253-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>315,782,786,27933,27934,41497,42566,51328</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26830430$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Garner, David M.</creatorcontrib><creatorcontrib>Anderson, Michael L.</creatorcontrib><creatorcontrib>Keiper, Christopher D.</creatorcontrib><creatorcontrib>Whynott, Rachel</creatorcontrib><creatorcontrib>Parker, Lisa</creatorcontrib><title>Psychotropic medications in adult and adolescent eating disorders: clinical practice versus evidence-based recommendations</title><title>Eating and weight disorders</title><addtitle>Eat Weight Disord</addtitle><addtitle>Eat Weight Disord</addtitle><description>Aim The current study examined the frequency of psychotropic prescriptions in a clinical sample of eating disorder (ED) patients confirming earlier research indicating their use is very common but inconsistent with evidence-based recommendations. Methods The sample consisted of 501 ED patients admitted to an adult partial hospitalization or adolescent residential program. Patients were divided into two diagnostic groups: anorexia nervosa (AN = 287) and bulimia nervosa (BN = 214), as well as two age groups: adults (age ≥18; N  = 318) and adolescents (age &lt;18; N  = 183). Results Forty-one different psychotropic medications (891 prescriptions in all) were prescribed for 429 patients. Overall, 85.6 % of the total sample reported using one or more psychotropic medications. Of 429 patients using any medications, 46.9 % were on two or more, 25.3 % on three or more, and 11.0 % four or more. Antidepressants were most commonly prescribed (89.5 % of those on medication) with no significant differences in usage patterns based on diagnosis. However, there was greater medication use among adults (89.6 %) compared to adolescents (78.7 %). Results indicate psychotropic medication prescription is more widespread in a clinical sample than in an earlier report screening for osteoporosis in AN women. Discussion Treatment recommendations suggest medication should not be the primary treatment for EDs and empirical evidence demonstrates their ineffectiveness in AN. Nevertheless, there were no differences in frequency found between diagnostic groups, confirming little relationship between evidence-based recommendations and actual clinical use for those referred to a specialized ED treatment facility. This study adds new evidence regarding age-based comparisons of psychotropic prescription frequency in clinical EDs and comparison between AN and BN which has not been examined in earlier studies.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Adults</subject><subject>Age</subject><subject>Antidepressive Agents - therapeutic use</subject><subject>Antipsychotic Agents - therapeutic use</subject><subject>Child</subject><subject>Eating disorders</subject><subject>Evidence-Based Medicine</subject><subject>Feeding and Eating Disorders - drug therapy</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Middle Aged</subject><subject>Original Article</subject><subject>Psychiatry</subject><subject>Psychotropic drugs</subject><subject>Psychotropic Drugs - therapeutic use</subject><subject>Teenagers</subject><subject>Treatment Outcome</subject><subject>Young Adult</subject><issn>1124-4909</issn><issn>1590-1262</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1UU9rFzEQDaLY-tMP4EUCXrxEJ5tsduNNSrWFgh70HPJntqbsJj-T3UL99KZsVRA8zZB5703mPUJecnjLAYZ3VULPNQOuGHS9YPCInPJeA-Od6h63nneSSQ36hDyr9QZAciHgKTnp1ChACjglP7_UO_89ryUfo6cLhujtGnOqNCZqwzav1KbQujxj9ZhWim2ermmINZeApb6nfo6p0WZ6LNav0SO9be9bpXgbAyaPzNmKgRb0eVkwhX3Dc_JksnPFFw_1QL59PP96dsGuPn-6PPtwxbwU48q4VEorO_h2jB0cToL7HvSknfOSO-f00MEgsLfoBt-KtnxUPox2GNzEe3Egb3bdY8k_NqyrWWI7ZZ5twrxVw0eulJCqeXMgr_-B3uStpPY700kYZXNbjw3Fd5QvudaCkzmWuNhyZziY-2DMHoxpwZj7YAw0zqsH5c01l_8wfifRAN0OqG2UrrH8Xf1_1V8RRprr</recordid><startdate>20160901</startdate><enddate>20160901</enddate><creator>Garner, David M.</creator><creator>Anderson, Michael L.</creator><creator>Keiper, Christopher D.</creator><creator>Whynott, Rachel</creator><creator>Parker, Lisa</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>7X8</scope></search><sort><creationdate>20160901</creationdate><title>Psychotropic medications in adult and adolescent eating disorders: clinical practice versus evidence-based recommendations</title><author>Garner, David M. ; Anderson, Michael L. ; Keiper, Christopher D. ; Whynott, Rachel ; Parker, Lisa</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c438t-146696a7c124a7bef31c509f9bbc41bbb972073e5aeb7ce5a9a186cd8a77bf153</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Adults</topic><topic>Age</topic><topic>Antidepressive Agents - therapeutic use</topic><topic>Antipsychotic Agents - therapeutic use</topic><topic>Child</topic><topic>Eating disorders</topic><topic>Evidence-Based Medicine</topic><topic>Feeding and Eating Disorders - drug therapy</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine &amp; Public Health</topic><topic>Middle Aged</topic><topic>Original Article</topic><topic>Psychiatry</topic><topic>Psychotropic drugs</topic><topic>Psychotropic Drugs - therapeutic use</topic><topic>Teenagers</topic><topic>Treatment Outcome</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Garner, David M.</creatorcontrib><creatorcontrib>Anderson, Michael L.</creatorcontrib><creatorcontrib>Keiper, Christopher D.</creatorcontrib><creatorcontrib>Whynott, Rachel</creatorcontrib><creatorcontrib>Parker, Lisa</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>MEDLINE - Academic</collection><jtitle>Eating and weight disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Garner, David M.</au><au>Anderson, Michael L.</au><au>Keiper, Christopher D.</au><au>Whynott, Rachel</au><au>Parker, Lisa</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Psychotropic medications in adult and adolescent eating disorders: clinical practice versus evidence-based recommendations</atitle><jtitle>Eating and weight disorders</jtitle><stitle>Eat Weight Disord</stitle><addtitle>Eat Weight Disord</addtitle><date>2016-09-01</date><risdate>2016</risdate><volume>21</volume><issue>3</issue><spage>395</spage><epage>402</epage><pages>395-402</pages><issn>1124-4909</issn><eissn>1590-1262</eissn><abstract>Aim The current study examined the frequency of psychotropic prescriptions in a clinical sample of eating disorder (ED) patients confirming earlier research indicating their use is very common but inconsistent with evidence-based recommendations. Methods The sample consisted of 501 ED patients admitted to an adult partial hospitalization or adolescent residential program. Patients were divided into two diagnostic groups: anorexia nervosa (AN = 287) and bulimia nervosa (BN = 214), as well as two age groups: adults (age ≥18; N  = 318) and adolescents (age &lt;18; N  = 183). Results Forty-one different psychotropic medications (891 prescriptions in all) were prescribed for 429 patients. Overall, 85.6 % of the total sample reported using one or more psychotropic medications. Of 429 patients using any medications, 46.9 % were on two or more, 25.3 % on three or more, and 11.0 % four or more. Antidepressants were most commonly prescribed (89.5 % of those on medication) with no significant differences in usage patterns based on diagnosis. However, there was greater medication use among adults (89.6 %) compared to adolescents (78.7 %). Results indicate psychotropic medication prescription is more widespread in a clinical sample than in an earlier report screening for osteoporosis in AN women. Discussion Treatment recommendations suggest medication should not be the primary treatment for EDs and empirical evidence demonstrates their ineffectiveness in AN. Nevertheless, there were no differences in frequency found between diagnostic groups, confirming little relationship between evidence-based recommendations and actual clinical use for those referred to a specialized ED treatment facility. This study adds new evidence regarding age-based comparisons of psychotropic prescription frequency in clinical EDs and comparison between AN and BN which has not been examined in earlier studies.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>26830430</pmid><doi>10.1007/s40519-016-0253-0</doi><tpages>8</tpages></addata></record>
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subjects Adolescent
Adult
Adults
Age
Antidepressive Agents - therapeutic use
Antipsychotic Agents - therapeutic use
Child
Eating disorders
Evidence-Based Medicine
Feeding and Eating Disorders - drug therapy
Female
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Original Article
Psychiatry
Psychotropic drugs
Psychotropic Drugs - therapeutic use
Teenagers
Treatment Outcome
Young Adult
title Psychotropic medications in adult and adolescent eating disorders: clinical practice versus evidence-based recommendations
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