Suppressors of Cytokine Signaling-1 and -6 Associate with and Inhibit the Insulin Receptor: A potantial mechanism for cytokine-mediated insulin resistance

Insulin resistance contributes to a number of metabolic disorders, including type II diabetes, hypertension, and atherosclerosis. Cytokines, such as tumor necrosis factor- alpha , interleukin-1 beta , and interleukin-6, and hormones, such as growth hormone, are known to cause insulin resistance, but...

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Veröffentlicht in:	The Journal of biological chemistry 2001-07, Vol.276 (28), p.25889-25893
Hauptverfasser:	Mooney, R A, Senn, J, Cameron, S, Inamdar, N, Boivin, L M, Shang, Y, Furlanetto, R W
Format:	Artikel
Sprache:	eng
Schlagworte:	insulin insulin receptors interleukin 1^b SOCS-1 protein SOCS-6 protein
Online-Zugang:	Volltext
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