Two useful dimensionless parameters that combine physiological, operational and bioreactor design parameters for improved control of dissolved oxygen
Two new dimensionless parameters (Φ and Ω) are proposed for calculating the proportional, integral, and derivative constants of a dissolved oxygen proportional integral-derivative (PID) feed-back control algorithm from knowledge of the growth rate, bioreactor design and operation variables. The valu...
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| Veröffentlicht in: | Biotechnology letters 2001-01, Vol.23 (13), p.1051-1056 |
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| container_issue | 13 |
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| container_title | Biotechnology letters |
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| creator | DE LEON, A BARBA-DE LA ROSA, A. P MAYANI, H GALINDO, E RAMIREZ, O. T |
| description | Two new dimensionless parameters (Φ and Ω) are proposed for calculating the proportional, integral, and derivative constants of a dissolved oxygen proportional integral-derivative (PID) feed-back control algorithm from knowledge of the growth rate, bioreactor design and operation variables. The values of Φ and Ω were determined for a broad range of Reynolds numbers (between 1000 to 40 000) during the exponential growth phase of two highly different processes: fermentations of recombinant Escherichia coli and cultures of human hematopoietic cells. The utility of Φ and Ω for use in dissolved oxygen self-tunning adaptive control algorithms is discussed.[PUBLICATION ABSTRACT] |
| doi_str_mv | 10.1023/A:1010598121587 |
| format | Article |
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P ; MAYANI, H ; GALINDO, E ; RAMIREZ, O. T</creator><creatorcontrib>DE LEON, A ; BARBA-DE LA ROSA, A. P ; MAYANI, H ; GALINDO, E ; RAMIREZ, O. T</creatorcontrib><description>Two new dimensionless parameters (Φ and Ω) are proposed for calculating the proportional, integral, and derivative constants of a dissolved oxygen proportional integral-derivative (PID) feed-back control algorithm from knowledge of the growth rate, bioreactor design and operation variables. The values of Φ and Ω were determined for a broad range of Reynolds numbers (between 1000 to 40 000) during the exponential growth phase of two highly different processes: fermentations of recombinant Escherichia coli and cultures of human hematopoietic cells. The utility of Φ and Ω for use in dissolved oxygen self-tunning adaptive control algorithms is discussed.[PUBLICATION ABSTRACT]</description><identifier>ISSN: 0141-5492</identifier><identifier>EISSN: 1573-6776</identifier><identifier>DOI: 10.1023/A:1010598121587</identifier><identifier>CODEN: BILED3</identifier><language>eng</language><publisher>Dordrecht: Springer</publisher><subject>Algorithms ; Bacteria ; Biological and medical sciences ; Bioreactors ; Biotechnology ; Control algorithms ; Dissolved oxygen ; E coli ; Escherichia coli ; Fundamental and applied biological sciences. Psychology ; Methods. Procedures. 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The utility of Φ and Ω for use in dissolved oxygen self-tunning adaptive control algorithms is discussed.[PUBLICATION ABSTRACT]</description><subject>Algorithms</subject><subject>Bacteria</subject><subject>Biological and medical sciences</subject><subject>Bioreactors</subject><subject>Biotechnology</subject><subject>Control algorithms</subject><subject>Dissolved oxygen</subject><subject>E coli</subject><subject>Escherichia coli</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Methods. Procedures. 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| subjects | Algorithms Bacteria Biological and medical sciences Bioreactors Biotechnology Control algorithms Dissolved oxygen E coli Escherichia coli Fundamental and applied biological sciences. Psychology Methods. Procedures. Technologies Microbiology Others Oxygen Various methods and equipments |
| title | Two useful dimensionless parameters that combine physiological, operational and bioreactor design parameters for improved control of dissolved oxygen |
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