Synthesis and structural insight into ESX-1 Substrate Protein C, an immunodominant Mycobacterium tuberculosis-secreted antigen

ABSTRACT Tuberculosis, the second leading cause of death from a single infectious agent, is recognized as a major threat to human health due to a lack of practicable vaccines against the disease and the widespread occurrence of drug resistance. With a pressing need for a novel protein target as a pl...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biopolymers 2016-05, Vol.106 (3), p.267-274
Hauptverfasser:	Son, Soo Jung, Harris, Paul W. R., Squire, Chris J., Baker, Edward N., Brimble, Margaret A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence antigen Antigens Antigens, Bacterial - chemistry Antigens, Bacterial - genetics Antigens, Bacterial - immunology Antigens, Differentiation, T-Lymphocyte - chemistry Antigens, Differentiation, T-Lymphocyte - immunology Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacterial Proteins - immunology Biopolymers Gene Expression Human Humans Mycobacterium mycobacterium tuberculosis Mycobacterium tuberculosis - chemistry Mycobacterium tuberculosis - immunology native chemical ligation Peptides - chemical synthesis Peptides - immunology Platforms Protein Folding Protein Structure, Secondary Proteins Solutions SPPS Substrates Tuberculosis Type VII Secretion Systems - genetics Vaccines
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!