Quantification of angiogenic sprouting under different growth factors in a microfluidic platform

Abstract Angiogenesis, as example of collective migration of endothelial cells (ECs), is the main dynamic process that culminates in sprout formation from existing vessels. After tissue injury, the vascularity is interrupted, triggering the regeneration process and the release of different growth fa...

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Veröffentlicht in:	Journal of biomechanics 2016-05, Vol.49 (8), p.1340-1346
Hauptverfasser:	Del Amo, Cristina, Borau, Carlos, Gutiérrez, Raquel, Asín, Jesús, García-Aznar, José Manuel
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Angiogenesis Bone Morphogenetic Protein 2 - physiology Cell culture Cell growth Collagen Collective Cell Migration Evolution Formations Growth factors Human Umbilical Vein Endothelial Cells - physiology Humans Hydrogels Matlab Microfluidics Molecular weight Neovascularization, Physiologic Permeability Physical Medicine and Rehabilitation Platelet-Derived Growth Factor - physiology Proteins Regenerative Sprouting Three dimensional Transforming Growth Factor beta - physiology Vascular endothelial growth factor Vascular Endothelial Growth Factor A - physiology
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