T1-Weighted MR imaging of liver tumor by gadolinium-encapsulated glycol chitosan nanoparticles without non-specific toxicity in normal tissues

Herein, we have synthesized Gd(iii)-encapsulated glycol chitosan nanoparticles (Gd(iii)-CNPs) for tumor-targeted T1-weighted magnetic resonance (MR) imaging. The T1 contrast agent, Gd(iii), was successfully encapsulated into 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA)-modified CN...

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Veröffentlicht in:	Nanoscale 2016-05, Vol.8 (18), p.9736-9745
Hauptverfasser:	Na, Jin Hee, Lee, Sangmin, Koo, Heebeom, Han, Hyounkoo, Lee, Kyung Eun, Han, Seung Jin, Choi, Seung Hong, Kim, Hyuncheol, Lee, Seulki, Kwon, Ick Chan, Choi, Kuiwon, Kim, Kwangmeyung
Format:	Artikel
Sprache:	eng
Schlagworte:	Chitosan Contrast agents Fluorescence Glycols Imaging Liver Nanoparticles Tumors
Online-Zugang:	Volltext
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