Human leukocyte antigen-G single nucleotide polymorphism -201 (CC-CC) donor-recipient genotype matching as a predictor of severe cardiac allograft vasculopathy

Background In heart transplant recipients, human leukocyte antigen (HLA)-G has been shown to inhibit endothelial and smooth muscle cells injury in vitro , suggesting protection against cardiac allograft vasculopathy (CAV). While the expression of HLA-G is regulated by single nucleotide polymorphisms...

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Veröffentlicht in:The Journal of heart and lung transplantation 2016-09, Vol.35 (9), p.1101-1107
Hauptverfasser: Lazarte, Julieta, Goldraich, Livia, Manlhiot, Cedric, Billia, Filio, Ross, Heather, Rao, Vivek, Delgado, Diego
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Sprache:eng
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