Lack of immunological DNA sensing in hepatocytes facilitates hepatitis B virus infection

Hepatitis B virus (HBV) is a major human pathogen, and about one third of the global population will be exposed to the virus in their lifetime. HBV infects hepatocytes, where it replicates its DNA and infection can lead to acute and chronic hepatitis with a high risk of liver cirrhosis and hepatocel...

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Veröffentlicht in:Hepatology (Baltimore, Md.) Md.), 2016-09, Vol.64 (3), p.746-759
Hauptverfasser: Thomsen, Martin K., Nandakumar, Ramya, Stadler, Daniela, Malo, Antje, Valls, Roser Marin, Wang, Fan, Reinert, Line S., Dagnæs‐Hansen, Frederik, Hollensen, Anne Kruse, Mikkelsen, Jacob Giehm, Protzer, Ulrike, Paludan, Søren R.
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Sprache:eng
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