Adenine attenuates the Ca super(2+) contraction-signaling pathway via adenine receptor-mediated signaling in rat vascular smooth muscle cells

Our previous study demonstrated that adenine (6-amino-6H-purine) relaxed contracted rat aorta rings in an endothelial-independent manner. Although adenine receptors (AdeRs) are expressed in diverse tissues, aortic AdeR expression has not been ascertained. Thus, the aims of this study were to clarify...

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Veröffentlicht in:Naunyn-Schmiedeberg's archives of pharmacology 2016-09, Vol.389 (9), p.999-1007
Hauptverfasser: Fukuda, Toshihiko, Kuroda, Takahiro, Kono, Miki, Hyoguchi, Mai, Tajiri, Satoshi, Tanaka, Mitsuru, Mine, Yoshinori, Matsui, Toshiro
Format: Artikel
Sprache:eng
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