Natural products and their derivatives as tRNA synthetase inhibitors and antimicrobial agents
The tRNA synthetase enzymes are promising targets for development of therapeutic agents against infections by parasitic protozoans ( e.g. malaria), fungi and yeast, as well as bacteria resistant to current antibiotics. These ubiquitous enzymes load a particular amino acid onto its cognate tRNA to fo...
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Veröffentlicht in: | MedChemComm 2016-08, Vol.7 (8), p.1535-1545 |
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Format: | Artikel |
Sprache: | eng |
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