Genome-wide analysis of tunicamycin-induced endoplasmic reticulum stress response and the protective effect of endoplasmic reticulum inhibitors in neonatal rat cardiomyocytes

Tunicamycin (TM) is an inducer of endoplasmic reticulum (ER) stress. However, which genes related to ER stress was induced in cardiomyocytes on a genome-wide scale remains poorly understood. Salubrinal and its derivatives are ER stress inhibitors. However, the cellular protection mechanisms remain u...

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Veröffentlicht in:	Molecular and cellular biochemistry 2016-02, Vol.413 (1-2), p.57-67
Hauptverfasser:	Liu, Chun-Lei, Zhong, Wu, He, Yun-Yun, Li, Xin, Li, Song, He, Kun-Lun
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Animals, Newborn Biochemistry Biomedical and Life Sciences Cardiology Cardiomyocytes Cells, Cultured Cinnamates - pharmacology Endoplasmic Reticulum Stress - drug effects Gene Expression - drug effects Gene Expression Profiling - methods Gene Expression Regulation - drug effects Genomes Genomics Heart cells Life Sciences Medical Biochemistry Myocytes, Cardiac - cytology Myocytes, Cardiac - drug effects Oncology Rats Ribonucleic acid RNA Rodents Sequence Analysis, RNA - methods Stress Thiourea - analogs & derivatives Thiourea - pharmacology Tunicamycin - pharmacology
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