HuR in pheochromocytomas and paragangliomas - overexpression in verified malignant tumors

Pheochromocytomas and paragangliomas are rare, neural crest‐originating, neuroendocrine tumors. HuR is an mRNA‐binding protein of the ELAV/Hu‐protein family, which participates in posttranscriptional regulation of many cancer‐associated genes. HuR expression has been connected with aggressive behavi...

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Veröffentlicht in:	APMIS : acta pathologica, microbiologica et immunologica Scandinavica microbiologica et immunologica Scandinavica, 2016-09, Vol.124 (9), p.757-763
Hauptverfasser:	Leijon, Helena, Salmenkivi, Kaisa, Heiskanen, Ilkka, Hagström, Jaana, Louhimo, Johanna, Heikkilä, Päivi, Ristimäki, Ari, Paavonen, Timo, Metso, Saara, Mäenpää, Hanna, Haglund, Caj, Arola, Johanna
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Nucleus - chemistry Cyclooxygenase 2 - analysis Cytoplasm - chemistry ELAV-Like Protein 1 - analysis Gene Expression Gene Expression Profiling Humans HuR Immunohistochemistry Metastasis Microarray Analysis Neoplasm Metastasis - pathology paraganglioma Paraganglioma - pathology Paraganglioma - secondary pheochromocytoma Pheochromocytoma - pathology Pheochromocytoma - secondary Proteins Tumors
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