TGF beta 1-Smad3-Jagged1-Notch1-Slug signaling pathway takes part in tumorigenesis and progress of tongue squamous cell carcinoma

Background TGF beta 1 and Smad3 play an important role in the process of EMT. TGF beta 1 regulates the expression of Jagged1 by modulating Notch signaling. Jagged1 is related to tumor invasion, metastasis, chemotherapy resistance, and tumor immune escape. The aims of this study are to examine deregu...

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Veröffentlicht in:	Journal of oral pathology & medicine 2016-08, Vol.45 (7), p.486-493
Hauptverfasser:	Zhang, Tonghan, Liang, Lizhong, Liu, Xiaoling, Wu, Ji-nan, Chen, Jueyao, Su, Kui, Zheng, Qiaoyi, Huang, Hongzhang, Liao, Gui-qing
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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