Resolvin D2 Enhances Postischemic Revascularization While Resolving Inflammation

BACKGROUND:Resolvins are lipid mediators generated by leukocytes during the resolution phase of inflammation. They have been shown to regulate the transition from inflammation to tissue repair; however, it is unknown whether resolvins play a role in tissue revascularization following ischemia. METHO...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2016-08, Vol.134 (9), p.666-680
Hauptverfasser:	Zhang, Michael J, Sansbury, Brian E, Hellmann, Jason, Baker, James F, Guo, Luping, Parmer, Caitlin M, Prenner, Joshua C, Conklin, Daniel J, Bhatnagar, Aruni, Creager, Mark A, Spite, Matthew
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cells, Cultured Cohort Studies Docosahexaenoic Acids - pharmacology Docosahexaenoic Acids - therapeutic use Female Hindlimb - blood supply Humans Inflammation - diagnosis Inflammation - drug therapy Inflammation - physiopathology Ischemia - drug therapy Ischemia - physiopathology Male Mice Mice, 129 Strain Mice, Inbred C57BL Mice, Knockout Mice, Obese Middle Aged Peripheral Arterial Disease - diagnosis Peripheral Arterial Disease - drug therapy Peripheral Arterial Disease - physiopathology
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