Are red blood cell transfusions associated with nosocomial infections in critically ill children?
Although the transfusionofblood products is common practice, its effects on the immune system have not been adequately studied. A prospective cohort study was conducted in critically ill children followed up until their death, transfer or discharge to establish an association between red blood cell...
Gespeichert in:
| Veröffentlicht in: | Archivos argentinos de pediatría 2016-08, Vol.114 (4), p.347-351 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng ; spa |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 351 |
|---|---|
| container_issue | 4 |
| container_start_page | 347 |
| container_title | Archivos argentinos de pediatría |
| container_volume | 114 |
| creator | Naveda Romero, Omar E Naveda Meléndez, Andrea F |
| description | Although the transfusionofblood products is common practice, its effects on the immune system have not been adequately studied. A prospective cohort study was conducted in critically ill children followed up until their death, transfer or discharge to establish an association between red blood cell transfusions (RBCTs) and nosocomial infections. A nosocomial infection was considered to be post-transfusional if it occurred within 14 days after RBCT. A total of 162 children were included in the study, 35 (21.6%) had a nosocomial infection, and 49 (30.2%) received a RBCT. Among those with a nosocomial infection, a RBCT was more common (48.5% versus 14.9%, OR: 5.4, 95% CI: 2.412.6, p 〈 0.0001) and mortality rate was higher (45.7% versus 10.2%, OR: 7.4, 95% CI: 3.1-18.2, p 〈 0.0001). The binary logistic regression showed that RBCT was independently associated with nosocomial infections (OR: 4.2, 95% CI: 2.1-20.2, p = 0.049).
RBCT was associated with increased risk for nosocomial infections. |
| doi_str_mv | 10.5546/aap.2016.347 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1815372083</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1815372083</sourcerecordid><originalsourceid>FETCH-LOGICAL-p562-b6e02df847148fc2a1cb66d95c0e9aa03655f1cd057313313270da038cfd7cd63</originalsourceid><addsrcrecordid>eNo1kM9LwzAUx4Mgbk5vniVHL5350STtScZwKgy87F5ek5RF0qQmLbL_3qoTHnx5Xz584D2E7ihZC1HKR4BhzQiVa16qC7SkUlYFF4Qu0HXOH4SUnNfqCi2Y4nVNKFsi2CSLkzW49TEarK33eEwQcjdlF0PGkHPUDsYZ-XLjEYc477F34LELndXjL-UC1smNToP3J-xmiT46b5INTzfosgOf7e05V-iwez5sX4v9-8vbdrMvBiFZ0UpLmOmqUtGy6jQDqlspTS00sTUA4VKIjmpDhOKUz8MUMXNd6c4obSRfoYc_7ZDi52Tz2PQu_5wDwcYpN7SigitGKj6j92d0antrmiG5HtKp-f8K_wZ3h2Lc</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1815372083</pqid></control><display><type>article</type><title>Are red blood cell transfusions associated with nosocomial infections in critically ill children?</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Naveda Romero, Omar E ; Naveda Meléndez, Andrea F</creator><creatorcontrib>Naveda Romero, Omar E ; Naveda Meléndez, Andrea F</creatorcontrib><description>Although the transfusionofblood products is common practice, its effects on the immune system have not been adequately studied. A prospective cohort study was conducted in critically ill children followed up until their death, transfer or discharge to establish an association between red blood cell transfusions (RBCTs) and nosocomial infections. A nosocomial infection was considered to be post-transfusional if it occurred within 14 days after RBCT. A total of 162 children were included in the study, 35 (21.6%) had a nosocomial infection, and 49 (30.2%) received a RBCT. Among those with a nosocomial infection, a RBCT was more common (48.5% versus 14.9%, OR: 5.4, 95% CI: 2.412.6, p 〈 0.0001) and mortality rate was higher (45.7% versus 10.2%, OR: 7.4, 95% CI: 3.1-18.2, p 〈 0.0001). The binary logistic regression showed that RBCT was independently associated with nosocomial infections (OR: 4.2, 95% CI: 2.1-20.2, p = 0.049).
RBCT was associated with increased risk for nosocomial infections.</description><identifier>EISSN: 1668-3501</identifier><identifier>DOI: 10.5546/aap.2016.347</identifier><identifier>PMID: 27399012</identifier><language>eng ; spa</language><publisher>Argentina</publisher><subject>Child ; Critical Illness ; Cross Infection - epidemiology ; Cross Infection - etiology ; Erythrocyte Transfusion - adverse effects ; Female ; Humans ; Male ; Prospective Studies</subject><ispartof>Archivos argentinos de pediatría, 2016-08, Vol.114 (4), p.347-351</ispartof><rights>Sociedad Argentina de Pediatría.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27399012$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Naveda Romero, Omar E</creatorcontrib><creatorcontrib>Naveda Meléndez, Andrea F</creatorcontrib><title>Are red blood cell transfusions associated with nosocomial infections in critically ill children?</title><title>Archivos argentinos de pediatría</title><addtitle>Arch Argent Pediatr</addtitle><description>Although the transfusionofblood products is common practice, its effects on the immune system have not been adequately studied. A prospective cohort study was conducted in critically ill children followed up until their death, transfer or discharge to establish an association between red blood cell transfusions (RBCTs) and nosocomial infections. A nosocomial infection was considered to be post-transfusional if it occurred within 14 days after RBCT. A total of 162 children were included in the study, 35 (21.6%) had a nosocomial infection, and 49 (30.2%) received a RBCT. Among those with a nosocomial infection, a RBCT was more common (48.5% versus 14.9%, OR: 5.4, 95% CI: 2.412.6, p 〈 0.0001) and mortality rate was higher (45.7% versus 10.2%, OR: 7.4, 95% CI: 3.1-18.2, p 〈 0.0001). The binary logistic regression showed that RBCT was independently associated with nosocomial infections (OR: 4.2, 95% CI: 2.1-20.2, p = 0.049).
RBCT was associated with increased risk for nosocomial infections.</description><subject>Child</subject><subject>Critical Illness</subject><subject>Cross Infection - epidemiology</subject><subject>Cross Infection - etiology</subject><subject>Erythrocyte Transfusion - adverse effects</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Prospective Studies</subject><issn>1668-3501</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kM9LwzAUx4Mgbk5vniVHL5350STtScZwKgy87F5ek5RF0qQmLbL_3qoTHnx5Xz584D2E7ihZC1HKR4BhzQiVa16qC7SkUlYFF4Qu0HXOH4SUnNfqCi2Y4nVNKFsi2CSLkzW49TEarK33eEwQcjdlF0PGkHPUDsYZ-XLjEYc477F34LELndXjL-UC1smNToP3J-xmiT46b5INTzfosgOf7e05V-iwez5sX4v9-8vbdrMvBiFZ0UpLmOmqUtGy6jQDqlspTS00sTUA4VKIjmpDhOKUz8MUMXNd6c4obSRfoYc_7ZDi52Tz2PQu_5wDwcYpN7SigitGKj6j92d0antrmiG5HtKp-f8K_wZ3h2Lc</recordid><startdate>20160801</startdate><enddate>20160801</enddate><creator>Naveda Romero, Omar E</creator><creator>Naveda Meléndez, Andrea F</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20160801</creationdate><title>Are red blood cell transfusions associated with nosocomial infections in critically ill children?</title><author>Naveda Romero, Omar E ; Naveda Meléndez, Andrea F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p562-b6e02df847148fc2a1cb66d95c0e9aa03655f1cd057313313270da038cfd7cd63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng ; spa</language><creationdate>2016</creationdate><topic>Child</topic><topic>Critical Illness</topic><topic>Cross Infection - epidemiology</topic><topic>Cross Infection - etiology</topic><topic>Erythrocyte Transfusion - adverse effects</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Prospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Naveda Romero, Omar E</creatorcontrib><creatorcontrib>Naveda Meléndez, Andrea F</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Archivos argentinos de pediatría</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Naveda Romero, Omar E</au><au>Naveda Meléndez, Andrea F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Are red blood cell transfusions associated with nosocomial infections in critically ill children?</atitle><jtitle>Archivos argentinos de pediatría</jtitle><addtitle>Arch Argent Pediatr</addtitle><date>2016-08-01</date><risdate>2016</risdate><volume>114</volume><issue>4</issue><spage>347</spage><epage>351</epage><pages>347-351</pages><eissn>1668-3501</eissn><abstract>Although the transfusionofblood products is common practice, its effects on the immune system have not been adequately studied. A prospective cohort study was conducted in critically ill children followed up until their death, transfer or discharge to establish an association between red blood cell transfusions (RBCTs) and nosocomial infections. A nosocomial infection was considered to be post-transfusional if it occurred within 14 days after RBCT. A total of 162 children were included in the study, 35 (21.6%) had a nosocomial infection, and 49 (30.2%) received a RBCT. Among those with a nosocomial infection, a RBCT was more common (48.5% versus 14.9%, OR: 5.4, 95% CI: 2.412.6, p 〈 0.0001) and mortality rate was higher (45.7% versus 10.2%, OR: 7.4, 95% CI: 3.1-18.2, p 〈 0.0001). The binary logistic regression showed that RBCT was independently associated with nosocomial infections (OR: 4.2, 95% CI: 2.1-20.2, p = 0.049).
RBCT was associated with increased risk for nosocomial infections.</abstract><cop>Argentina</cop><pmid>27399012</pmid><doi>10.5546/aap.2016.347</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | EISSN: 1668-3501 |
| ispartof | Archivos argentinos de pediatría, 2016-08, Vol.114 (4), p.347-351 |
| issn | 1668-3501 |
| language | eng ; spa |
| recordid | cdi_proquest_miscellaneous_1815372083 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Child Critical Illness Cross Infection - epidemiology Cross Infection - etiology Erythrocyte Transfusion - adverse effects Female Humans Male Prospective Studies |
| title | Are red blood cell transfusions associated with nosocomial infections in critically ill children? |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-11T10%3A11%3A36IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Are%20red%20blood%20cell%20transfusions%20associated%20with%20nosocomial%20infections%20in%20critically%20ill%20children?&rft.jtitle=Archivos%20argentinos%20de%20pediatr%C3%ADa&rft.au=Naveda%20Romero,%20Omar%20E&rft.date=2016-08-01&rft.volume=114&rft.issue=4&rft.spage=347&rft.epage=351&rft.pages=347-351&rft.eissn=1668-3501&rft_id=info:doi/10.5546/aap.2016.347&rft_dat=%3Cproquest_pubme%3E1815372083%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1815372083&rft_id=info:pmid/27399012&rfr_iscdi=true |