Utility of Induced Sputum in Routine Clinical Practice

To determine the general and specific utility in diagnosis and/or treatment of induced sputum (IS) inflammatory cell counts in routine clinical practice. Retrospective study of 171 patients referred for clinical sputum induction over a 1-year period in the pulmonology department of a referral hospit...

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Veröffentlicht in:	Archivos de bronconeumología (English ed.) 2016-05, Vol.52 (5), p.250-255
Hauptverfasser:	Barril, Silvia, Sebastián, Laura, Cotta, Gianluca, Crespo, Astrid, Mateus, Eder, Torrejón, Montserrat, Ramos-Barbón, David, Plaza, Vicente
Format:	Artikel
Sprache:	eng ; spa
Schlagworte:	Adult Aged Asthma - drug therapy Asthma - pathology Clinical Decision-Making Cough - pathology Female Gastroesophageal Reflux - pathology Hospital Departments Humans Inflammation Leukocyte Count Male Middle Aged Nebulizers and Vaporizers Retrospective Studies Saline Solution, Hypertonic - pharmacology Salivation - drug effects Sputum - cytology
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container_title	Archivos de bronconeumología (English ed.)
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creator	Barril, Silvia Sebastián, Laura Cotta, Gianluca Crespo, Astrid Mateus, Eder Torrejón, Montserrat Ramos-Barbón, David Plaza, Vicente
description	To determine the general and specific utility in diagnosis and/or treatment of induced sputum (IS) inflammatory cell counts in routine clinical practice. Retrospective study of 171 patients referred for clinical sputum induction over a 1-year period in the pulmonology department of a referral hospital. Independent observers established whether the information provided by IS inflammatory cell count was useful for making diagnostic and therapeutic decisions. The most frequent reasons for determination of IS inflammatory cell count were: asthma 103 (59.20%); uncontrolled asthma 34 (19.54%); chronic cough 19 (10.9%), and gastroesophageal reflux 15 (8.6%). In 115 patients (67.3%) it was generally useful for diagnosis and/or treatment; in 98 patients (57.3%) it provided diagnostic information and in 85 patients (49.7%) it assisted in therapeutic decision-making. In asthma, uncontrolled asthma, chronic cough and gastroesophageal reflux, the results were useful in 71.8%, 67.6%, 47.4% and 60%, respectively. The information provided by IS inflammatory cell count is extremely useful in clinical practice, especially in asthma and chronic cough. These results may justify the inclusion of the IS technique in pulmonology departments and asthma units of referral centers.
doi_str_mv	10.1016/j.arbres.2015.10.002
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Retrospective study of 171 patients referred for clinical sputum induction over a 1-year period in the pulmonology department of a referral hospital. Independent observers established whether the information provided by IS inflammatory cell count was useful for making diagnostic and therapeutic decisions. The most frequent reasons for determination of IS inflammatory cell count were: asthma 103 (59.20%); uncontrolled asthma 34 (19.54%); chronic cough 19 (10.9%), and gastroesophageal reflux 15 (8.6%). In 115 patients (67.3%) it was generally useful for diagnosis and/or treatment; in 98 patients (57.3%) it provided diagnostic information and in 85 patients (49.7%) it assisted in therapeutic decision-making. In asthma, uncontrolled asthma, chronic cough and gastroesophageal reflux, the results were useful in 71.8%, 67.6%, 47.4% and 60%, respectively. The information provided by IS inflammatory cell count is extremely useful in clinical practice, especially in asthma and chronic cough. 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Retrospective study of 171 patients referred for clinical sputum induction over a 1-year period in the pulmonology department of a referral hospital. Independent observers established whether the information provided by IS inflammatory cell count was useful for making diagnostic and therapeutic decisions. The most frequent reasons for determination of IS inflammatory cell count were: asthma 103 (59.20%); uncontrolled asthma 34 (19.54%); chronic cough 19 (10.9%), and gastroesophageal reflux 15 (8.6%). In 115 patients (67.3%) it was generally useful for diagnosis and/or treatment; in 98 patients (57.3%) it provided diagnostic information and in 85 patients (49.7%) it assisted in therapeutic decision-making. In asthma, uncontrolled asthma, chronic cough and gastroesophageal reflux, the results were useful in 71.8%, 67.6%, 47.4% and 60%, respectively. The information provided by IS inflammatory cell count is extremely useful in clinical practice, especially in asthma and chronic cough. 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source	Elsevier ScienceDirect Journals Complete - AutoHoldings; MEDLINE
subjects	Adult Aged Asthma - drug therapy Asthma - pathology Clinical Decision-Making Cough - pathology Female Gastroesophageal Reflux - pathology Hospital Departments Humans Inflammation Leukocyte Count Male Middle Aged Nebulizers and Vaporizers Retrospective Studies Saline Solution, Hypertonic - pharmacology Salivation - drug effects Sputum - cytology
title	Utility of Induced Sputum in Routine Clinical Practice
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