Paraphaeosphaeride D and berkleasmin F, new circumventors of arbekacin resistance in MRSA, produced by Paraphaeosphaeria sp. TR-022

Two new compounds, designated paraphaeosphaeride D ( 1 ) and berkleasmin F ( 2 ) together with a previously known compound, berkleasmin A ( 3 ), isolated from a culture broth of the fungus Paraphaeosphaeria sp. TR-022, proved to be new circumventors of arbekacin (ABK) resistance in methicillin-resis...

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Veröffentlicht in:	Journal of antibiotics 2016-08, Vol.69 (8), p.605-610
Hauptverfasser:	Suga, Takuya, Shiina, Mayu, Asami, Yukihiro, Iwatsuki, Masato, Yamamoto, Tsuyoshi, Nonaka, Kenichi, Masuma, Rokuro, Matsui, Hidehito, Hanaki, Hideaki, Iwamoto, Susumu, Onodera, Hideyuki, Shiomi, Kazuro, Ōmura, Satoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	631/326/22/1290 639/638/403/936 Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology Ascomycota - metabolism Bacteriology Biomedical and Life Sciences Bioorganic Chemistry Dibekacin - analogs & derivatives Dibekacin - pharmacology Drug Resistance, Bacterial Lactams - chemistry Lactams - isolation & purification Lactams - pharmacology Life Sciences Magnetic Resonance Spectroscopy Medicinal Chemistry Methicillin-Resistant Staphylococcus aureus - drug effects Microbial Sensitivity Tests Microbiology Organic Chemistry original-article Pyrones - chemistry Pyrones - isolation & purification Pyrones - pharmacology Sesquiterpenes - chemistry Sesquiterpenes - isolation & purification Sesquiterpenes - pharmacology
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