Dermatological side effects of intravesical Mitomycin C: Delayed hypersensitivity

To know the dermatologic side effects of intravesical treatment with Mitomycin C in non muscle invasive bladder cancer. We describe two cases of palm and plantar dermatitis after such treatment. We describe two types of dermatitis pathogenesis during treatment with intravesical Mitomycin C: contact dermatitis and delayed hypersensitivity dermatitis. Contact dermatitis of non-allergic origin is a common side effect described in many instances in the literature, on the other hand exists dermatitis secondary to delayed hypersensitivity type IV much less common, requiring treatment with corticosteroids.