Probing the performance limits of the Escherichia coli metabolic network subject to gene additions or deletions
An optimization‐based procedure for studying the response of metabolic networks after gene knockouts or additions is introduced and applied to a linear flux balance analysis (FBA) Escherichia coli model. Both the gene addition problem of optimally selecting which foreign genes to recombine into E. c...
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Veröffentlicht in: | Biotechnology and bioengineering 2001-09, Vol.74 (5), p.364-375 |
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Sprache: | eng |
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