Fascin 1 promoted the growth and migration of non-small cell lung cancer cells by activating YAP/TEAD signaling

Fascin 1 (Fascin actin-bundling protein 1) is an actin-binding protein. Although several studies have reported the dysregulation of Fascin 1 in non-small cell lung cancer (NSCLC), its functions in the progression of NSCLC and the related molecular mechanism were not fully understood. In this study,...

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Veröffentlicht in:	Tumor biology 2016-08, Vol.37 (8), p.10909-10915
Hauptverfasser:	Liang, Zhigang, Wang, Ying, Shen, Zhenya, Teng, Xiaomei, Li, Xinjian, Li, Chenwei, Wu, Weijie, Zhou, Zenghui, Wang, Zishan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - metabolism Biomedical and Life Sciences Biomedicine Blotting, Western Cancer Research Carcinoma, Non-Small-Cell Lung - metabolism Carcinoma, Non-Small-Cell Lung - pathology Carrier Proteins - metabolism Cell adhesion & migration Cell growth Cell Line, Tumor Cell Movement - physiology Cell Proliferation - physiology DNA-Binding Proteins - metabolism Gene Expression Regulation, Neoplastic - physiology Gene Knockdown Techniques Humans Immunohistochemistry Immunoprecipitation Lung cancer Lung Neoplasms - metabolism Lung Neoplasms - pathology Microfilament Proteins - metabolism Nuclear Proteins - metabolism Original Article Phosphoproteins - metabolism Real-Time Polymerase Chain Reaction Signal Transduction - physiology Studies Transcription Factors - metabolism
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