Application of Coiled Coil Peptides in Liposomal Anticancer Drug Delivery Using a Zebrafish Xenograft Model

The complementary coiled coil forming peptides E4 [(EIAALEK)4] and K4 [(KIAALKE)4] are known to trigger liposomal membrane fusion when tethered to lipid vesicles in the form of lipopeptides. In this study, we examined whether these coiled coil forming peptides can be used for drug delivery applicati...

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Veröffentlicht in:	ACS nano 2016-08, Vol.10 (8), p.7428-7435
Hauptverfasser:	Yang, Jian, Shimada, Yasuhito, Olsthoorn, René C. L, Snaar-Jagalska, B. Ewa, Spaink, Herman P, Kros, Alexander
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line, Tumor Doxorubicin - administration & dosage Drug Delivery Systems HeLa Cells Heterografts Humans Liposomes Peptides Zebrafish
Online-Zugang:	Volltext
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