Palladium-Catalyzed Intramolecular Dearomatization of Indoles via Decarboxylative Alkynyl Termination

A highly diastereoselective dearomatization of indoles via palladium-catalyzed decarboxylative alkynyl termination was developed. This protocol provides dissimilar tetracyclic and tetrasubstituted indoline scaffolds bearing congested stereocenters, which led to operationally simple conditions, short...

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Veröffentlicht in:Organic letters 2016-08, Vol.18 (16), p.4016-4019
Hauptverfasser: Chen, Si, Wu, Xin-Xing, Wang, Jia, Hao, Xin-Hua, Xia, Yu, Shen, Yi, Jing, Huanwang, Liang, Yong-Min
Format: Artikel
Sprache:eng
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