Disruptions of the Ustilago maydis REC2 gene identify a protein domain important in directing recombinational repair of DNA

The REC2 gene of Ustilago maydis encodes a homologue of the Escherichia coli RecA protein and was first identified in a screen for UV‐sensitive mutants. The original isolate, rec2‐1, was found to be deficient in repair of DNA damage, genetic recombination and meiosis. We report here that the rec2‐19...

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Veröffentlicht in:	Molecular microbiology 2001-06, Vol.40 (6), p.1415-1426
Hauptverfasser:	Kojic, Milorad, Thompson, Chad W., Holloman, William K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Binding Sites Chromosome Segregation Diploidy DNA Repair - drug effects DNA Repair - genetics DNA Repair - radiation effects Fungal Proteins - genetics Fungal Proteins - metabolism Homozygote Meiosis Methyl Methanesulfonate - pharmacology Molecular Sequence Data Mutagens - pharmacology Mutation Protein Structure, Tertiary Rad51 protein REC2 gene Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Recombination, Genetic Spores, Fungal - physiology Two-Hybrid System Techniques Ultraviolet Rays Ustilago - drug effects Ustilago - physiology Ustilago - radiation effects Ustilago maydis Yeasts - genetics
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