Control of Wnt5b secretion by Wntless modulates chondrogenic cell proliferation through fine-tuning fgf3 expression

Wnts and Fgfs regulate various tissues development in vertebrates. However, how regional Wnt or Fgf activities are established and how they interact in any given developmental event is elusive. Here, we investigated the Wnt-mediated craniofacial cartilage development in zebrafish and found that fgf3...

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Veröffentlicht in:	Journal of cell science 2015-06, Vol.128 (12), p.2328-2339
Hauptverfasser:	Wu, Bo-Tsung, Wen, Shih-Hsien, Hwang, Sheng-Ping L, Huang, Chang-Jen, Kuan, Yung-Shu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Cartilage - growth & development Cartilage - metabolism Cell Proliferation Cells, Cultured Chondrogenesis - physiology Danio rerio Embryo, Nonmammalian - cytology Embryo, Nonmammalian - metabolism Embryonic Development Fibroblast Growth Factor 3 - metabolism Gene Expression Regulation, Developmental Immunoenzyme Techniques In Situ Hybridization Morpholinos - pharmacology Receptors, G-Protein-Coupled - metabolism Wnt Proteins - metabolism Wnt-5a Protein Zebrafish - embryology Zebrafish - metabolism Zebrafish Proteins - metabolism
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