Identification of Oncogenic and Drug-Sensitizing Mutations in the Extracellular Domain of FGFR2

The discovery of oncogenic driver mutations and the subsequent developments in targeted therapies have led to improved outcomes for subsets of lung cancer patients. The identification of additional oncogenic and drug-sensitive alterations may similarly lead to new therapeutic approaches for lung can...

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Veröffentlicht in:Cancer research (Chicago, Ill.) Ill.), 2015-08, Vol.75 (15), p.3139-3146
Hauptverfasser: Tanizaki, Junko, Ercan, Dalia, Capelletti, Marzia, Dodge, Michael, Xu, Chunxiao, Bahcall, Magda, Tricker, Erin M, Butaney, Mohit, Calles, Antonio, Sholl, Lynette M, Hammerman, Peter S, Oxnard, Geoffrey R, Wong, Kwok-Kin, Jänne, Pasi A
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Sprache:eng
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