Comparison of Transradial and Transfemoral Approaches for Percutaneous Coronary Intervention in Patients with Acute Coronary Syndrome and Anemia
Abstract Anemia is an independent predictor of bleeding complications and poor clinical outcomes after percutaneous coronary intervention. Percutaneous coronary transradial intervention (TRI) is better than percutaneous coronary transfemoral intervention (TFI) in terms of reducing bleeding complicat...
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| Veröffentlicht in: | The American journal of cardiology 2016-05, Vol.117 (10), p.1582-1587 |
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| creator | Lee, Seung Hun, MD Jeong, Myung Ho, MD Han, Kyoo RoK., MD Sim, Doo Sun, MD Yoon, Junghan, MD Youn, Young Jin, MD Cho, Byung Ryeol, MD Cha, Kwang Soo, MD Hyon, Min Su, MD Rha, Seung Woon, MD Kim, Byung Ok, MD Shin, Won Yong, MD Park, Keum Soo, MD Cheong, Sang Sig, MD |
| description | Abstract Anemia is an independent predictor of bleeding complications and poor clinical outcomes after percutaneous coronary intervention. Percutaneous coronary transradial intervention (TRI) is better than percutaneous coronary transfemoral intervention (TFI) in terms of reducing bleeding complications that can affect the prognosis. This study aims to investigate the clinical outcomes between TRI and TFI for patients with anemia. We analyzed peri-procedure complications, in-hospital mortality, and major adverse cardiac events for one year in the Korean TRI registry from January 2013 to April 2014. Patients with chronic kidney disease for whom TFI is preferred were excluded. Anemia was defined as hemoglobin |
| doi_str_mv | 10.1016/j.amjcard.2016.02.030 |
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| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1811907355</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0002914916302909</els_id><sourcerecordid>4050345561</sourcerecordid><originalsourceid>FETCH-LOGICAL-c481t-67f0f09077c86adac5509e18cffb89fd409a11c5d20b96172712e233c6bed32f3</originalsourceid><addsrcrecordid>eNqFksFu1DAQhiMEotvCI4AiceGS4HE2sX0BrVYUKlWiUsvZ8tpj1SGxFzvbat-CR8bbLFTqpSd7rO__RzO_i-IdkBoIdJ_6Wo29VtHUNJc1oTVpyItiAZyJCgQ0L4sFIYRWApbipDhNqc8lQNu9Lk4oI8BFQxfFn3UYtyq6FHwZbHkTlU9RGaeGUnkz1xbHEPPDaruNQelbTKUNsbzCqHeT8hh2qVyHGLyK-_LCTxjv0E8uOzpfXqnJ5SqV9266LVdZgY_w9d6bGEZ86LXyODr1pnhl1ZDw7fE8K36ef71Zf68uf3y7WK8uK73kMFUds8QSQRjTvFNG6bYlAoFrazdcWLMkQgHo1lCyER0wyoAibRrdbdA01DZnxcfZN8_0e4dpkqNLGodhHkgCB8j2Tds-jzLOCG85ZRn98ATtwy76PMgDxRhhnGaqnSkdQ0oRrdxGN-aFSCDykK7s5TFdeUhXEipzuln3_ui-24xo_qv-xZmBLzOAeXN3DqNMOm9fo3ER9SRNcM-2-PzEQQ_OO62GX7jH9DiNTFkgrw9f7PDDoGvyhYjmL3FCzrY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1787770782</pqid></control><display><type>article</type><title>Comparison of Transradial and Transfemoral Approaches for Percutaneous Coronary Intervention in Patients with Acute Coronary Syndrome and Anemia</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Lee, Seung Hun, MD ; Jeong, Myung Ho, MD ; Han, Kyoo RoK., MD ; Sim, Doo Sun, MD ; Yoon, Junghan, MD ; Youn, Young Jin, MD ; Cho, Byung Ryeol, MD ; Cha, Kwang Soo, MD ; Hyon, Min Su, MD ; Rha, Seung Woon, MD ; Kim, Byung Ok, MD ; Shin, Won Yong, MD ; Park, Keum Soo, MD ; Cheong, Sang Sig, MD</creator><creatorcontrib>Lee, Seung Hun, MD ; Jeong, Myung Ho, MD ; Han, Kyoo RoK., MD ; Sim, Doo Sun, MD ; Yoon, Junghan, MD ; Youn, Young Jin, MD ; Cho, Byung Ryeol, MD ; Cha, Kwang Soo, MD ; Hyon, Min Su, MD ; Rha, Seung Woon, MD ; Kim, Byung Ok, MD ; Shin, Won Yong, MD ; Park, Keum Soo, MD ; Cheong, Sang Sig, MD ; Korean Transradial Coronary Intervention Registry Investigators</creatorcontrib><description>Abstract Anemia is an independent predictor of bleeding complications and poor clinical outcomes after percutaneous coronary intervention. Percutaneous coronary transradial intervention (TRI) is better than percutaneous coronary transfemoral intervention (TFI) in terms of reducing bleeding complications that can affect the prognosis. This study aims to investigate the clinical outcomes between TRI and TFI for patients with anemia. We analyzed peri-procedure complications, in-hospital mortality, and major adverse cardiac events for one year in the Korean TRI registry from January 2013 to April 2014. Patients with chronic kidney disease for whom TFI is preferred were excluded. Anemia was defined as hemoglobin <13 g/dL for men and <12 g/dL for women. A total of 1,279 patients were finally enrolled. Of these, 348 patients had anemia. Among them, 253 (72.7%) patients underwent TRI and 95 (27.3%) patients underwent TFI. There were no significant differences of baseline demographic characteristics between the TRI and TFI groups, except for the incidence of dyslipidemia (TRI 23.7% vs. TFT 12.6%, P=0.023). Multivariate logistic regression analysis revealed lower incidence of composite severe bleeding complications [Hazard ratio (HR) 0.34, 95% confidential interval (CI) 0.12-0.99, P=0.049], and lower incidence of in-hospital mortality than TFI group (HR=0.74, 95% CI 0.62-0.88, P=0.042). In conclusion, this study suggests that the TRI for patients with anemia may be translated into better prognosis in terms of lower rates of bleeding complications and in-hospital mortality.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/j.amjcard.2016.02.030</identifier><identifier>PMID: 27018932</identifier><identifier>CODEN: AJCDAG</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Acute Coronary Syndrome - mortality ; Acute Coronary Syndrome - surgery ; Acute coronary syndromes ; Aged ; Anemia ; Anemia - epidemiology ; Anemia - etiology ; Blood pressure ; Cardiology ; Cardiovascular ; Cardiovascular disease ; Cholesterol ; Clinical outcomes ; Confidence intervals ; Feasibility Studies ; Female ; Femoral Artery ; Follow-Up Studies ; Heart attacks ; Hospital Mortality - trends ; Hospitalization ; Humans ; Incidence ; Kinases ; Laboratories ; Lipoproteins ; Logistics ; Male ; Molecular weight ; Mortality ; Percutaneous Coronary Intervention - adverse effects ; Percutaneous Coronary Intervention - methods ; Postoperative Hemorrhage - complications ; Postoperative Hemorrhage - epidemiology ; Prognosis ; Prospective Studies ; Radial Artery ; Registries ; Regression analysis ; Republic of Korea - epidemiology ; Risk factors ; Survival analysis ; Veins & arteries</subject><ispartof>The American journal of cardiology, 2016-05, Vol.117 (10), p.1582-1587</ispartof><rights>Elsevier Inc.</rights><rights>2016 Elsevier Inc.</rights><rights>Copyright © 2016 Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Limited May 15, 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c481t-67f0f09077c86adac5509e18cffb89fd409a11c5d20b96172712e233c6bed32f3</citedby><cites>FETCH-LOGICAL-c481t-67f0f09077c86adac5509e18cffb89fd409a11c5d20b96172712e233c6bed32f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0002914916302909$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27018932$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lee, Seung Hun, MD</creatorcontrib><creatorcontrib>Jeong, Myung Ho, MD</creatorcontrib><creatorcontrib>Han, Kyoo RoK., MD</creatorcontrib><creatorcontrib>Sim, Doo Sun, MD</creatorcontrib><creatorcontrib>Yoon, Junghan, MD</creatorcontrib><creatorcontrib>Youn, Young Jin, MD</creatorcontrib><creatorcontrib>Cho, Byung Ryeol, MD</creatorcontrib><creatorcontrib>Cha, Kwang Soo, MD</creatorcontrib><creatorcontrib>Hyon, Min Su, MD</creatorcontrib><creatorcontrib>Rha, Seung Woon, MD</creatorcontrib><creatorcontrib>Kim, Byung Ok, MD</creatorcontrib><creatorcontrib>Shin, Won Yong, MD</creatorcontrib><creatorcontrib>Park, Keum Soo, MD</creatorcontrib><creatorcontrib>Cheong, Sang Sig, MD</creatorcontrib><creatorcontrib>Korean Transradial Coronary Intervention Registry Investigators</creatorcontrib><title>Comparison of Transradial and Transfemoral Approaches for Percutaneous Coronary Intervention in Patients with Acute Coronary Syndrome and Anemia</title><title>The American journal of cardiology</title><addtitle>Am J Cardiol</addtitle><description>Abstract Anemia is an independent predictor of bleeding complications and poor clinical outcomes after percutaneous coronary intervention. Percutaneous coronary transradial intervention (TRI) is better than percutaneous coronary transfemoral intervention (TFI) in terms of reducing bleeding complications that can affect the prognosis. This study aims to investigate the clinical outcomes between TRI and TFI for patients with anemia. We analyzed peri-procedure complications, in-hospital mortality, and major adverse cardiac events for one year in the Korean TRI registry from January 2013 to April 2014. Patients with chronic kidney disease for whom TFI is preferred were excluded. Anemia was defined as hemoglobin <13 g/dL for men and <12 g/dL for women. A total of 1,279 patients were finally enrolled. Of these, 348 patients had anemia. Among them, 253 (72.7%) patients underwent TRI and 95 (27.3%) patients underwent TFI. There were no significant differences of baseline demographic characteristics between the TRI and TFI groups, except for the incidence of dyslipidemia (TRI 23.7% vs. TFT 12.6%, P=0.023). Multivariate logistic regression analysis revealed lower incidence of composite severe bleeding complications [Hazard ratio (HR) 0.34, 95% confidential interval (CI) 0.12-0.99, P=0.049], and lower incidence of in-hospital mortality than TFI group (HR=0.74, 95% CI 0.62-0.88, P=0.042). In conclusion, this study suggests that the TRI for patients with anemia may be translated into better prognosis in terms of lower rates of bleeding complications and in-hospital mortality.</description><subject>Acute Coronary Syndrome - mortality</subject><subject>Acute Coronary Syndrome - surgery</subject><subject>Acute coronary syndromes</subject><subject>Aged</subject><subject>Anemia</subject><subject>Anemia - epidemiology</subject><subject>Anemia - etiology</subject><subject>Blood pressure</subject><subject>Cardiology</subject><subject>Cardiovascular</subject><subject>Cardiovascular disease</subject><subject>Cholesterol</subject><subject>Clinical outcomes</subject><subject>Confidence intervals</subject><subject>Feasibility Studies</subject><subject>Female</subject><subject>Femoral Artery</subject><subject>Follow-Up Studies</subject><subject>Heart attacks</subject><subject>Hospital Mortality - trends</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Incidence</subject><subject>Kinases</subject><subject>Laboratories</subject><subject>Lipoproteins</subject><subject>Logistics</subject><subject>Male</subject><subject>Molecular weight</subject><subject>Mortality</subject><subject>Percutaneous Coronary Intervention - adverse effects</subject><subject>Percutaneous Coronary Intervention - methods</subject><subject>Postoperative Hemorrhage - complications</subject><subject>Postoperative Hemorrhage - epidemiology</subject><subject>Prognosis</subject><subject>Prospective Studies</subject><subject>Radial Artery</subject><subject>Registries</subject><subject>Regression analysis</subject><subject>Republic of Korea - epidemiology</subject><subject>Risk factors</subject><subject>Survival analysis</subject><subject>Veins & arteries</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFksFu1DAQhiMEotvCI4AiceGS4HE2sX0BrVYUKlWiUsvZ8tpj1SGxFzvbat-CR8bbLFTqpSd7rO__RzO_i-IdkBoIdJ_6Wo29VtHUNJc1oTVpyItiAZyJCgQ0L4sFIYRWApbipDhNqc8lQNu9Lk4oI8BFQxfFn3UYtyq6FHwZbHkTlU9RGaeGUnkz1xbHEPPDaruNQelbTKUNsbzCqHeT8hh2qVyHGLyK-_LCTxjv0E8uOzpfXqnJ5SqV9266LVdZgY_w9d6bGEZ86LXyODr1pnhl1ZDw7fE8K36ef71Zf68uf3y7WK8uK73kMFUds8QSQRjTvFNG6bYlAoFrazdcWLMkQgHo1lCyER0wyoAibRrdbdA01DZnxcfZN8_0e4dpkqNLGodhHkgCB8j2Tds-jzLOCG85ZRn98ATtwy76PMgDxRhhnGaqnSkdQ0oRrdxGN-aFSCDykK7s5TFdeUhXEipzuln3_ui-24xo_qv-xZmBLzOAeXN3DqNMOm9fo3ER9SRNcM-2-PzEQQ_OO62GX7jH9DiNTFkgrw9f7PDDoGvyhYjmL3FCzrY</recordid><startdate>20160515</startdate><enddate>20160515</enddate><creator>Lee, Seung Hun, MD</creator><creator>Jeong, Myung Ho, MD</creator><creator>Han, Kyoo RoK., MD</creator><creator>Sim, Doo Sun, MD</creator><creator>Yoon, Junghan, MD</creator><creator>Youn, Young Jin, MD</creator><creator>Cho, Byung Ryeol, MD</creator><creator>Cha, Kwang Soo, MD</creator><creator>Hyon, Min Su, MD</creator><creator>Rha, Seung Woon, MD</creator><creator>Kim, Byung Ok, MD</creator><creator>Shin, Won Yong, MD</creator><creator>Park, Keum Soo, MD</creator><creator>Cheong, Sang Sig, MD</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7Z</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20160515</creationdate><title>Comparison of Transradial and Transfemoral Approaches for Percutaneous Coronary Intervention in Patients with Acute Coronary Syndrome and Anemia</title><author>Lee, Seung Hun, MD ; Jeong, Myung Ho, MD ; Han, Kyoo RoK., MD ; Sim, Doo Sun, MD ; Yoon, Junghan, MD ; Youn, Young Jin, MD ; Cho, Byung Ryeol, MD ; Cha, Kwang Soo, MD ; Hyon, Min Su, MD ; Rha, Seung Woon, MD ; Kim, Byung Ok, MD ; Shin, Won Yong, MD ; Park, Keum Soo, MD ; Cheong, Sang Sig, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c481t-67f0f09077c86adac5509e18cffb89fd409a11c5d20b96172712e233c6bed32f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Acute Coronary Syndrome - mortality</topic><topic>Acute Coronary Syndrome - surgery</topic><topic>Acute coronary syndromes</topic><topic>Aged</topic><topic>Anemia</topic><topic>Anemia - epidemiology</topic><topic>Anemia - etiology</topic><topic>Blood pressure</topic><topic>Cardiology</topic><topic>Cardiovascular</topic><topic>Cardiovascular disease</topic><topic>Cholesterol</topic><topic>Clinical outcomes</topic><topic>Confidence intervals</topic><topic>Feasibility Studies</topic><topic>Female</topic><topic>Femoral Artery</topic><topic>Follow-Up Studies</topic><topic>Heart attacks</topic><topic>Hospital Mortality - trends</topic><topic>Hospitalization</topic><topic>Humans</topic><topic>Incidence</topic><topic>Kinases</topic><topic>Laboratories</topic><topic>Lipoproteins</topic><topic>Logistics</topic><topic>Male</topic><topic>Molecular weight</topic><topic>Mortality</topic><topic>Percutaneous Coronary Intervention - adverse effects</topic><topic>Percutaneous Coronary Intervention - methods</topic><topic>Postoperative Hemorrhage - complications</topic><topic>Postoperative Hemorrhage - epidemiology</topic><topic>Prognosis</topic><topic>Prospective Studies</topic><topic>Radial Artery</topic><topic>Registries</topic><topic>Regression analysis</topic><topic>Republic of Korea - epidemiology</topic><topic>Risk factors</topic><topic>Survival analysis</topic><topic>Veins & arteries</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lee, Seung Hun, MD</creatorcontrib><creatorcontrib>Jeong, Myung Ho, MD</creatorcontrib><creatorcontrib>Han, Kyoo RoK., MD</creatorcontrib><creatorcontrib>Sim, Doo Sun, MD</creatorcontrib><creatorcontrib>Yoon, Junghan, MD</creatorcontrib><creatorcontrib>Youn, Young Jin, MD</creatorcontrib><creatorcontrib>Cho, Byung Ryeol, MD</creatorcontrib><creatorcontrib>Cha, Kwang Soo, MD</creatorcontrib><creatorcontrib>Hyon, Min Su, MD</creatorcontrib><creatorcontrib>Rha, Seung Woon, MD</creatorcontrib><creatorcontrib>Kim, Byung Ok, MD</creatorcontrib><creatorcontrib>Shin, Won Yong, MD</creatorcontrib><creatorcontrib>Park, Keum Soo, MD</creatorcontrib><creatorcontrib>Cheong, Sang Sig, MD</creatorcontrib><creatorcontrib>Korean Transradial Coronary Intervention Registry Investigators</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Physical Education Index</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Biochemistry Abstracts 1</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lee, Seung Hun, MD</au><au>Jeong, Myung Ho, MD</au><au>Han, Kyoo RoK., MD</au><au>Sim, Doo Sun, MD</au><au>Yoon, Junghan, MD</au><au>Youn, Young Jin, MD</au><au>Cho, Byung Ryeol, MD</au><au>Cha, Kwang Soo, MD</au><au>Hyon, Min Su, MD</au><au>Rha, Seung Woon, MD</au><au>Kim, Byung Ok, MD</au><au>Shin, Won Yong, MD</au><au>Park, Keum Soo, MD</au><au>Cheong, Sang Sig, MD</au><aucorp>Korean Transradial Coronary Intervention Registry Investigators</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of Transradial and Transfemoral Approaches for Percutaneous Coronary Intervention in Patients with Acute Coronary Syndrome and Anemia</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>2016-05-15</date><risdate>2016</risdate><volume>117</volume><issue>10</issue><spage>1582</spage><epage>1587</epage><pages>1582-1587</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>Abstract Anemia is an independent predictor of bleeding complications and poor clinical outcomes after percutaneous coronary intervention. Percutaneous coronary transradial intervention (TRI) is better than percutaneous coronary transfemoral intervention (TFI) in terms of reducing bleeding complications that can affect the prognosis. This study aims to investigate the clinical outcomes between TRI and TFI for patients with anemia. We analyzed peri-procedure complications, in-hospital mortality, and major adverse cardiac events for one year in the Korean TRI registry from January 2013 to April 2014. Patients with chronic kidney disease for whom TFI is preferred were excluded. Anemia was defined as hemoglobin <13 g/dL for men and <12 g/dL for women. A total of 1,279 patients were finally enrolled. Of these, 348 patients had anemia. Among them, 253 (72.7%) patients underwent TRI and 95 (27.3%) patients underwent TFI. There were no significant differences of baseline demographic characteristics between the TRI and TFI groups, except for the incidence of dyslipidemia (TRI 23.7% vs. TFT 12.6%, P=0.023). Multivariate logistic regression analysis revealed lower incidence of composite severe bleeding complications [Hazard ratio (HR) 0.34, 95% confidential interval (CI) 0.12-0.99, P=0.049], and lower incidence of in-hospital mortality than TFI group (HR=0.74, 95% CI 0.62-0.88, P=0.042). In conclusion, this study suggests that the TRI for patients with anemia may be translated into better prognosis in terms of lower rates of bleeding complications and in-hospital mortality.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>27018932</pmid><doi>10.1016/j.amjcard.2016.02.030</doi><tpages>6</tpages></addata></record> |
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| subjects | Acute Coronary Syndrome - mortality Acute Coronary Syndrome - surgery Acute coronary syndromes Aged Anemia Anemia - epidemiology Anemia - etiology Blood pressure Cardiology Cardiovascular Cardiovascular disease Cholesterol Clinical outcomes Confidence intervals Feasibility Studies Female Femoral Artery Follow-Up Studies Heart attacks Hospital Mortality - trends Hospitalization Humans Incidence Kinases Laboratories Lipoproteins Logistics Male Molecular weight Mortality Percutaneous Coronary Intervention - adverse effects Percutaneous Coronary Intervention - methods Postoperative Hemorrhage - complications Postoperative Hemorrhage - epidemiology Prognosis Prospective Studies Radial Artery Registries Regression analysis Republic of Korea - epidemiology Risk factors Survival analysis Veins & arteries |
| title | Comparison of Transradial and Transfemoral Approaches for Percutaneous Coronary Intervention in Patients with Acute Coronary Syndrome and Anemia |
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