Exome-based proteogenomics of HEK-293 human cell line: Coding genomic variants identified at the level of shotgun proteome

Genomic and proteomic data were integrated into the proteogenomic workflow to identify coding genomic variants of Human Embryonic Kidney 293 (HEK‐293) cell line at the proteome level. Shotgun proteome data published by Geiger et al. (2012), Chick et al. (2015), and obtained in this work for HEK‐293...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proteomics (Weinheim) 2016-07, Vol.16 (14), p.1980-1991
Hauptverfasser:	Lobas, Anna A., Karpov, Dmitry S., Kopylov, Arthur T., Solovyeva, Elizaveta M., Ivanov, Mark V., Ilina, Irina Y., Lazarev, Vassily N., Kuznetsova, Ksenia G., Ilgisonis, Ekaterina V., Zgoda, Victor G., Gorshkov, Mikhail V., Moshkovskii, Sergei A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino acids Bioinformatics Cancer Datasets Datasets as Topic Exome Gene Ontology Genomics HEK-293 cell line HEK293 Cells Humans Molecular Sequence Annotation Mutation Neoplasm Proteins - genetics Neoplasm Proteins - isolation & purification Neoplasm Proteins - metabolism p53 Protein Passengers Peptides Polymorphism, Genetic Proteins Proteogenomics Proteome - genetics Proteome - isolation & purification Proteome - metabolism Proteomics Proteomics - methods Shotgun proteomics Single nucleotide variant Tumor suppressor genes Tumor Suppressor Protein p53 - genetics Tumor Suppressor Protein p53 - isolation & purification Tumor Suppressor Protein p53 - metabolism Workflow
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!