Loading of Gemcitabine on chitosan magnetic nanoparticles increases the anti-cancer efficacy of the drug

Targeted delivery of anti-cancer drugs increase the efficacy, while decreasing adverse effects. Among various delivery systems, chitosan coated iron oxide nanoparticles (CsMNPs) gained attention with their biocompatibility, biodegradability, low toxicity and targetability under magnetic field. This...

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Veröffentlicht in:	European journal of pharmacology 2016-08, Vol.784, p.121-128
Hauptverfasser:	Parsian, Maryam, Unsoy, Gozde, Mutlu, Pelin, Yalcin, Serap, Tezcaner, Aysen, Gunduz, Ufuk
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Biological Transport Breast cancer Cell Line, Tumor Chitosan Chitosan - chemistry Chitosan - metabolism Deoxycytidine - analogs & derivatives Deoxycytidine - chemistry Deoxycytidine - pharmacology Drug Carriers - chemistry Drug Carriers - metabolism Drug Liberation Gemcitabine Humans Magnetic Fields Magnetic nanoparticles Magnetite Nanoparticles - chemistry MCF-7 Cells Targeted drug delivery
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