Applying theoretical premises of binary toxicity mathematical modeling to combined impacts of chemical plus physical agents (A case study of moderate subchronic exposures to fluoride and static magnetic field)

Sodium fluoride solution was injected i.p. to rats at a dose equivalent to 0.1 LD50 three times a week up to 18 injections. Two thirds of these rats and of the sham-injected ones were exposed to the whole body impact of a 25 mT static magnetic field for 2 or 4 h a day, 5 times a week. For mathematic...

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Veröffentlicht in:	Food and chemical toxicology 2016-09, Vol.95, p.110-120
Hauptverfasser:	Katsnelson, B.A., Tsepilov, N.A., Panov, V.G., Sutunkova, M.P., Varaksin, A.N., Gurvich, V.B., Minigalieva, I.A., Valamina, I.E., Makeyev, O.H., Meshtcheryakova, E.Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Combined adverse action Drug Evaluation Female Fluoride Magnetic Fields - adverse effects Models, Theoretical Rats Risk Assessment Sodium Fluoride - toxicity Static magnetic field Toxicity Tests, Subchronic - methods
Online-Zugang:	Volltext
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