Usefulness of Diastolic Strain Measurements in Predicting Elevated Left Ventricular Filling Pressure and Risk of Rejection or Coronary Artery Vasculopathy in Pediatric Heart Transplant Recipients
In pediatric heart transplant recipients, elevated pulmonary capillary wedge pressure (PCWP) is associated with rejection and coronary artery vasculopathy. This study aimed to evaluate which echocardiographic parameters track changes in PCWP and predict adverse outcomes (rejection or coronary artery...
Gespeichert in:
| Veröffentlicht in: | The American journal of cardiology 2016-05, Vol.117 (9), p.1533-1538 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1538 |
|---|---|
| container_issue | 9 |
| container_start_page | 1533 |
| container_title | The American journal of cardiology |
| container_volume | 117 |
| creator | Lu, Jimmy C., MD Magdo, H. Sonali, MD Yu, Sunkyung, MS Lowery, Ray, BS Aiyagari, Ranjit, MD Zamberlan, Mary, MS, CPNP Gajarski, Robert J., MD |
| description | In pediatric heart transplant recipients, elevated pulmonary capillary wedge pressure (PCWP) is associated with rejection and coronary artery vasculopathy. This study aimed to evaluate which echocardiographic parameters track changes in PCWP and predict adverse outcomes (rejection or coronary artery vasculopathy). This prospective single-center study enrolled 49 patients (median 11.4 years old, interquartile range 7.4 to 16.5) at time of cardiac catheterization and echocardiography. Median follow-up was 2.4 years (range 1.2 to 3.1 years), with serial testing per clinical protocol. Ratio of early mitral inflow to annular velocity (E/E′), left atrial (LA) distensibility, peak LA systolic strain, E/left ventricular (LV) diastolic strain, and E/LV diastolic strain rate were measured from echocardiograms. Increase in PCWP ≥3 mm Hg was associated with changes in LA distensibility, E/E′, and E/LV diastolic strain, with highest area under the receiver operating characteristic curve for E/LV diastolic strain (0.76). In 9 patients who subsequently developed rejection or coronary artery vasculopathy, E/LV diastolic strain rate at baseline differed from patients without events (median 57.0 vs 43.6, p = 0.02). On serial studies, only change in LV ejection fraction differed in patients with events (median −10% vs −1%, p = 0.01); decrease in LV ejection fraction of −19% had a specificity of 100% and sensitivity of 44%. In conclusion, LV diastolic strain and strain rate measurements can track changes in PCWP and identify patients at risk for subsequent rejection or coronary artery vasculopathy. Further studies are necessary to confirm these data in a larger cohort. |
| doi_str_mv | 10.1016/j.amjcard.2016.02.009 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1811898881</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0002914916302223</els_id><sourcerecordid>1780509321</sourcerecordid><originalsourceid>FETCH-LOGICAL-c481t-9352ba3100eca96c1b8e16fd3440e549587707607f841be15a35ff31be0c58f83</originalsourceid><addsrcrecordid>eNqFkstuEzEUhkcIREPhEUCW2LBJ8GUu9gZUhV6QgkDpZWs5njPg6WQcbE-lvE2fpVLfizNNAKmbruwjfec_tz_L3jI6Y5SVH9uZWbfWhHrGMZxRPqNUPcsmTFZqyhQTz7MJpZRPFcvVQfYqxhZDxoryZXbAS1WVleKT7P4yQjN0PcRIfEO-OBOT75wl5ykY15NvYOIQYA19igTjHwFqZ5Prf5LjDm5MgposoEnkCong7NCZQE5c140EwnHMJqavydLFayxxd7uEFlDB98QHMvfB9yZsyVFIgM-ViajhNyb92j7Uw3JmFCZnYEK6u70Ipo-bzvSJLMG6jRs7e529aEwX4c3-PcwuT44v5mfTxffTr_OjxdTmkqWpEgVfGcEoBWtUadlKAiubWuQ5hSJXhawqWpW0amTOVsAKI4qmEfiltpCNFIfZh53uJvjfA8Sk1y5a6LAd8EPUTDImlZSSPY1WkhZUCT6i7x-hrR9Cj4M8UBI7khSpYkfZ4GMM0OhNcGtcnWZUj5bQrd5bQo-W0JRrtATmvdurD6s11P-y_noAgc87AHBzNw6Cjha3anHzAQ-la--eLPHpkYLF-ztrumvYQvw_jY6YoM9HX462ZKWgnHMh_gAQneOf</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1780876080</pqid></control><display><type>article</type><title>Usefulness of Diastolic Strain Measurements in Predicting Elevated Left Ventricular Filling Pressure and Risk of Rejection or Coronary Artery Vasculopathy in Pediatric Heart Transplant Recipients</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Lu, Jimmy C., MD ; Magdo, H. Sonali, MD ; Yu, Sunkyung, MS ; Lowery, Ray, BS ; Aiyagari, Ranjit, MD ; Zamberlan, Mary, MS, CPNP ; Gajarski, Robert J., MD</creator><creatorcontrib>Lu, Jimmy C., MD ; Magdo, H. Sonali, MD ; Yu, Sunkyung, MS ; Lowery, Ray, BS ; Aiyagari, Ranjit, MD ; Zamberlan, Mary, MS, CPNP ; Gajarski, Robert J., MD</creatorcontrib><description>In pediatric heart transplant recipients, elevated pulmonary capillary wedge pressure (PCWP) is associated with rejection and coronary artery vasculopathy. This study aimed to evaluate which echocardiographic parameters track changes in PCWP and predict adverse outcomes (rejection or coronary artery vasculopathy). This prospective single-center study enrolled 49 patients (median 11.4 years old, interquartile range 7.4 to 16.5) at time of cardiac catheterization and echocardiography. Median follow-up was 2.4 years (range 1.2 to 3.1 years), with serial testing per clinical protocol. Ratio of early mitral inflow to annular velocity (E/E′), left atrial (LA) distensibility, peak LA systolic strain, E/left ventricular (LV) diastolic strain, and E/LV diastolic strain rate were measured from echocardiograms. Increase in PCWP ≥3 mm Hg was associated with changes in LA distensibility, E/E′, and E/LV diastolic strain, with highest area under the receiver operating characteristic curve for E/LV diastolic strain (0.76). In 9 patients who subsequently developed rejection or coronary artery vasculopathy, E/LV diastolic strain rate at baseline differed from patients without events (median 57.0 vs 43.6, p = 0.02). On serial studies, only change in LV ejection fraction differed in patients with events (median −10% vs −1%, p = 0.01); decrease in LV ejection fraction of −19% had a specificity of 100% and sensitivity of 44%. In conclusion, LV diastolic strain and strain rate measurements can track changes in PCWP and identify patients at risk for subsequent rejection or coronary artery vasculopathy. Further studies are necessary to confirm these data in a larger cohort.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/j.amjcard.2016.02.009</identifier><identifier>PMID: 26976792</identifier><identifier>CODEN: AJCDAG</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adolescent ; Anesthesia ; Biopsy ; Cardiovascular ; Cardiovascular disease ; Catheters ; Child ; Child, Preschool ; Cohort Studies ; Coronary Artery Disease - diagnosis ; Coronary Artery Disease - etiology ; Coronary vessels ; Female ; Graft Rejection - etiology ; Heart attacks ; Heart Failure, Diastolic - diagnosis ; Heart Failure, Diastolic - physiopathology ; Heart Failure, Diastolic - surgery ; Heart Transplantation - adverse effects ; Humans ; Intubation ; Male ; Pediatrics ; Predictive Value of Tests ; Pulmonary Wedge Pressure - physiology ; ROC Curve ; Software ; Stroke Volume - physiology ; Studies ; Transplants & implants ; Variables ; Velocity</subject><ispartof>The American journal of cardiology, 2016-05, Vol.117 (9), p.1533-1538</ispartof><rights>Elsevier Inc.</rights><rights>2016 Elsevier Inc.</rights><rights>Copyright © 2016 Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Limited May 1, 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c481t-9352ba3100eca96c1b8e16fd3440e549587707607f841be15a35ff31be0c58f83</citedby><cites>FETCH-LOGICAL-c481t-9352ba3100eca96c1b8e16fd3440e549587707607f841be15a35ff31be0c58f83</cites><orcidid>0000-0002-2544-7402 ; 0000-0002-0193-0344 ; 0000-0001-9358-2967</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0002914916302223$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26976792$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lu, Jimmy C., MD</creatorcontrib><creatorcontrib>Magdo, H. Sonali, MD</creatorcontrib><creatorcontrib>Yu, Sunkyung, MS</creatorcontrib><creatorcontrib>Lowery, Ray, BS</creatorcontrib><creatorcontrib>Aiyagari, Ranjit, MD</creatorcontrib><creatorcontrib>Zamberlan, Mary, MS, CPNP</creatorcontrib><creatorcontrib>Gajarski, Robert J., MD</creatorcontrib><title>Usefulness of Diastolic Strain Measurements in Predicting Elevated Left Ventricular Filling Pressure and Risk of Rejection or Coronary Artery Vasculopathy in Pediatric Heart Transplant Recipients</title><title>The American journal of cardiology</title><addtitle>Am J Cardiol</addtitle><description>In pediatric heart transplant recipients, elevated pulmonary capillary wedge pressure (PCWP) is associated with rejection and coronary artery vasculopathy. This study aimed to evaluate which echocardiographic parameters track changes in PCWP and predict adverse outcomes (rejection or coronary artery vasculopathy). This prospective single-center study enrolled 49 patients (median 11.4 years old, interquartile range 7.4 to 16.5) at time of cardiac catheterization and echocardiography. Median follow-up was 2.4 years (range 1.2 to 3.1 years), with serial testing per clinical protocol. Ratio of early mitral inflow to annular velocity (E/E′), left atrial (LA) distensibility, peak LA systolic strain, E/left ventricular (LV) diastolic strain, and E/LV diastolic strain rate were measured from echocardiograms. Increase in PCWP ≥3 mm Hg was associated with changes in LA distensibility, E/E′, and E/LV diastolic strain, with highest area under the receiver operating characteristic curve for E/LV diastolic strain (0.76). In 9 patients who subsequently developed rejection or coronary artery vasculopathy, E/LV diastolic strain rate at baseline differed from patients without events (median 57.0 vs 43.6, p = 0.02). On serial studies, only change in LV ejection fraction differed in patients with events (median −10% vs −1%, p = 0.01); decrease in LV ejection fraction of −19% had a specificity of 100% and sensitivity of 44%. In conclusion, LV diastolic strain and strain rate measurements can track changes in PCWP and identify patients at risk for subsequent rejection or coronary artery vasculopathy. Further studies are necessary to confirm these data in a larger cohort.</description><subject>Adolescent</subject><subject>Anesthesia</subject><subject>Biopsy</subject><subject>Cardiovascular</subject><subject>Cardiovascular disease</subject><subject>Catheters</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Cohort Studies</subject><subject>Coronary Artery Disease - diagnosis</subject><subject>Coronary Artery Disease - etiology</subject><subject>Coronary vessels</subject><subject>Female</subject><subject>Graft Rejection - etiology</subject><subject>Heart attacks</subject><subject>Heart Failure, Diastolic - diagnosis</subject><subject>Heart Failure, Diastolic - physiopathology</subject><subject>Heart Failure, Diastolic - surgery</subject><subject>Heart Transplantation - adverse effects</subject><subject>Humans</subject><subject>Intubation</subject><subject>Male</subject><subject>Pediatrics</subject><subject>Predictive Value of Tests</subject><subject>Pulmonary Wedge Pressure - physiology</subject><subject>ROC Curve</subject><subject>Software</subject><subject>Stroke Volume - physiology</subject><subject>Studies</subject><subject>Transplants & implants</subject><subject>Variables</subject><subject>Velocity</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkstuEzEUhkcIREPhEUCW2LBJ8GUu9gZUhV6QgkDpZWs5njPg6WQcbE-lvE2fpVLfizNNAKmbruwjfec_tz_L3jI6Y5SVH9uZWbfWhHrGMZxRPqNUPcsmTFZqyhQTz7MJpZRPFcvVQfYqxhZDxoryZXbAS1WVleKT7P4yQjN0PcRIfEO-OBOT75wl5ykY15NvYOIQYA19igTjHwFqZ5Prf5LjDm5MgposoEnkCong7NCZQE5c140EwnHMJqavydLFayxxd7uEFlDB98QHMvfB9yZsyVFIgM-ViajhNyb92j7Uw3JmFCZnYEK6u70Ipo-bzvSJLMG6jRs7e529aEwX4c3-PcwuT44v5mfTxffTr_OjxdTmkqWpEgVfGcEoBWtUadlKAiubWuQ5hSJXhawqWpW0amTOVsAKI4qmEfiltpCNFIfZh53uJvjfA8Sk1y5a6LAd8EPUTDImlZSSPY1WkhZUCT6i7x-hrR9Cj4M8UBI7khSpYkfZ4GMM0OhNcGtcnWZUj5bQrd5bQo-W0JRrtATmvdurD6s11P-y_noAgc87AHBzNw6Cjha3anHzAQ-la--eLPHpkYLF-ztrumvYQvw_jY6YoM9HX462ZKWgnHMh_gAQneOf</recordid><startdate>20160501</startdate><enddate>20160501</enddate><creator>Lu, Jimmy C., MD</creator><creator>Magdo, H. Sonali, MD</creator><creator>Yu, Sunkyung, MS</creator><creator>Lowery, Ray, BS</creator><creator>Aiyagari, Ranjit, MD</creator><creator>Zamberlan, Mary, MS, CPNP</creator><creator>Gajarski, Robert J., MD</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7Z</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-2544-7402</orcidid><orcidid>https://orcid.org/0000-0002-0193-0344</orcidid><orcidid>https://orcid.org/0000-0001-9358-2967</orcidid></search><sort><creationdate>20160501</creationdate><title>Usefulness of Diastolic Strain Measurements in Predicting Elevated Left Ventricular Filling Pressure and Risk of Rejection or Coronary Artery Vasculopathy in Pediatric Heart Transplant Recipients</title><author>Lu, Jimmy C., MD ; Magdo, H. Sonali, MD ; Yu, Sunkyung, MS ; Lowery, Ray, BS ; Aiyagari, Ranjit, MD ; Zamberlan, Mary, MS, CPNP ; Gajarski, Robert J., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c481t-9352ba3100eca96c1b8e16fd3440e549587707607f841be15a35ff31be0c58f83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adolescent</topic><topic>Anesthesia</topic><topic>Biopsy</topic><topic>Cardiovascular</topic><topic>Cardiovascular disease</topic><topic>Catheters</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Cohort Studies</topic><topic>Coronary Artery Disease - diagnosis</topic><topic>Coronary Artery Disease - etiology</topic><topic>Coronary vessels</topic><topic>Female</topic><topic>Graft Rejection - etiology</topic><topic>Heart attacks</topic><topic>Heart Failure, Diastolic - diagnosis</topic><topic>Heart Failure, Diastolic - physiopathology</topic><topic>Heart Failure, Diastolic - surgery</topic><topic>Heart Transplantation - adverse effects</topic><topic>Humans</topic><topic>Intubation</topic><topic>Male</topic><topic>Pediatrics</topic><topic>Predictive Value of Tests</topic><topic>Pulmonary Wedge Pressure - physiology</topic><topic>ROC Curve</topic><topic>Software</topic><topic>Stroke Volume - physiology</topic><topic>Studies</topic><topic>Transplants & implants</topic><topic>Variables</topic><topic>Velocity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lu, Jimmy C., MD</creatorcontrib><creatorcontrib>Magdo, H. Sonali, MD</creatorcontrib><creatorcontrib>Yu, Sunkyung, MS</creatorcontrib><creatorcontrib>Lowery, Ray, BS</creatorcontrib><creatorcontrib>Aiyagari, Ranjit, MD</creatorcontrib><creatorcontrib>Zamberlan, Mary, MS, CPNP</creatorcontrib><creatorcontrib>Gajarski, Robert J., MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Physical Education Index</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Biochemistry Abstracts 1</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lu, Jimmy C., MD</au><au>Magdo, H. Sonali, MD</au><au>Yu, Sunkyung, MS</au><au>Lowery, Ray, BS</au><au>Aiyagari, Ranjit, MD</au><au>Zamberlan, Mary, MS, CPNP</au><au>Gajarski, Robert J., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Usefulness of Diastolic Strain Measurements in Predicting Elevated Left Ventricular Filling Pressure and Risk of Rejection or Coronary Artery Vasculopathy in Pediatric Heart Transplant Recipients</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>2016-05-01</date><risdate>2016</risdate><volume>117</volume><issue>9</issue><spage>1533</spage><epage>1538</epage><pages>1533-1538</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>In pediatric heart transplant recipients, elevated pulmonary capillary wedge pressure (PCWP) is associated with rejection and coronary artery vasculopathy. This study aimed to evaluate which echocardiographic parameters track changes in PCWP and predict adverse outcomes (rejection or coronary artery vasculopathy). This prospective single-center study enrolled 49 patients (median 11.4 years old, interquartile range 7.4 to 16.5) at time of cardiac catheterization and echocardiography. Median follow-up was 2.4 years (range 1.2 to 3.1 years), with serial testing per clinical protocol. Ratio of early mitral inflow to annular velocity (E/E′), left atrial (LA) distensibility, peak LA systolic strain, E/left ventricular (LV) diastolic strain, and E/LV diastolic strain rate were measured from echocardiograms. Increase in PCWP ≥3 mm Hg was associated with changes in LA distensibility, E/E′, and E/LV diastolic strain, with highest area under the receiver operating characteristic curve for E/LV diastolic strain (0.76). In 9 patients who subsequently developed rejection or coronary artery vasculopathy, E/LV diastolic strain rate at baseline differed from patients without events (median 57.0 vs 43.6, p = 0.02). On serial studies, only change in LV ejection fraction differed in patients with events (median −10% vs −1%, p = 0.01); decrease in LV ejection fraction of −19% had a specificity of 100% and sensitivity of 44%. In conclusion, LV diastolic strain and strain rate measurements can track changes in PCWP and identify patients at risk for subsequent rejection or coronary artery vasculopathy. Further studies are necessary to confirm these data in a larger cohort.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>26976792</pmid><doi>10.1016/j.amjcard.2016.02.009</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0002-2544-7402</orcidid><orcidid>https://orcid.org/0000-0002-0193-0344</orcidid><orcidid>https://orcid.org/0000-0001-9358-2967</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0002-9149 |
| ispartof | The American journal of cardiology, 2016-05, Vol.117 (9), p.1533-1538 |
| issn | 0002-9149 1879-1913 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1811898881 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adolescent Anesthesia Biopsy Cardiovascular Cardiovascular disease Catheters Child Child, Preschool Cohort Studies Coronary Artery Disease - diagnosis Coronary Artery Disease - etiology Coronary vessels Female Graft Rejection - etiology Heart attacks Heart Failure, Diastolic - diagnosis Heart Failure, Diastolic - physiopathology Heart Failure, Diastolic - surgery Heart Transplantation - adverse effects Humans Intubation Male Pediatrics Predictive Value of Tests Pulmonary Wedge Pressure - physiology ROC Curve Software Stroke Volume - physiology Studies Transplants & implants Variables Velocity |
| title | Usefulness of Diastolic Strain Measurements in Predicting Elevated Left Ventricular Filling Pressure and Risk of Rejection or Coronary Artery Vasculopathy in Pediatric Heart Transplant Recipients |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T11%3A42%3A38IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Usefulness%20of%20Diastolic%20Strain%20Measurements%20in%20Predicting%20Elevated%20Left%20Ventricular%20Filling%20Pressure%20and%20Risk%20of%C2%A0Rejection%20or%20Coronary%20Artery%20Vasculopathy%20in%20Pediatric%20Heart%C2%A0Transplant%20Recipients&rft.jtitle=The%20American%20journal%20of%20cardiology&rft.au=Lu,%20Jimmy%20C.,%20MD&rft.date=2016-05-01&rft.volume=117&rft.issue=9&rft.spage=1533&rft.epage=1538&rft.pages=1533-1538&rft.issn=0002-9149&rft.eissn=1879-1913&rft.coden=AJCDAG&rft_id=info:doi/10.1016/j.amjcard.2016.02.009&rft_dat=%3Cproquest_cross%3E1780509321%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1780876080&rft_id=info:pmid/26976792&rft_els_id=S0002914916302223&rfr_iscdi=true |