Platelet hyperaggregability in obesity: is there a role for nitric oxide impairment and oxidative stress?

Summary Epidemiological evidence has shown that platelet activation markers are consistently elevated in obesity, contributing to its prothrombotic state. In order to improve the understanding of the regulation of platelet function in obesity, the aim of this study was to investigate the l‐arginine‐...

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Veröffentlicht in:	Clinical and experimental pharmacology & physiology 2016-08, Vol.43 (8), p.738-744
Hauptverfasser:	Leite, Natália Rodrigues Pereira, Siqueira de Medeiros, Mariana, Mury, Wanda Vianna, Matsuura, Cristiane, Perszel, Monique Bandeira Moss, Noronha Filho, Gerson, Brunini, Tatiana MC, Mendes-Ribeiro, Antônio Claúdio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Arginine - blood Blood Platelets - metabolism cardiovascular disease Cross-Sectional Studies Cyclic GMP - blood Female Humans Male Middle Aged nitric oxide Nitric Oxide - metabolism Nitric Oxide Synthase - blood obesity Obesity - blood Obesity - diagnosis oxidative stress Oxidative Stress - physiology Platelet Aggregation - physiology platelets
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